Human HBB/CD113t-C/HBD ORF/cDNA clone-Lentivirus plasmid (BC007075)

Cat. No.: pGMLP000401
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human HBB/CD113t-C/HBD Lentiviral expression plasmid for HBB lentivirus packaging, HBB lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000401
Gene Name HBB
Accession Number BC007075
Gene ID 3043
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 444 bp
Gene Alias CD113t-C,HBD
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGTGCACCTGACTCCTGAGGAGAAGTCTGCCGTTACTGCCCTGTGGGGCAAGGTGAACGTGGATGAAGTTGGTGGTGAGGCCCTGGGCAGGCTGCTGGTGGTCTACCCTTGGACCCAGAGGTTCTTTGAGTCCTTTGGGGATCTGTCCACCCCTGATGCTGTTATGGGCAACCCTAAGGTGAAGGCTCATGGCAAGAAAGTGCTCGGTGCCTTTAGTGATGGCCTGGCTCACCTGGACAACCTCAAGGGCACCTTTGCCACACTGAGTGAGCTGCACTGTGACAAGCTGCACGTGGATCCTGAGAACTTCAGGCTCCTGGGCAACGTGCTGGTCTGTGTGCTGGCCCATCACTTTGGCAAAGAATTCACCCCACCAGTGCAGGCTGCCTATCAGAAAGTGGTGGCTGGTGTGGCTAATGCCCTGGCCCACAAGTATCACTAA
ORF Protein Sequence MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T31825-Ab Anti-HBB monoclonal antibody
    Target Antigen GM-Tg-g-T31825-Ag HBB protein
    ORF Viral Vector pGMLP000401 Human HBB Lentivirus plasmid
    ORF Viral Vector pGMAP000026 Human HBB Adenovirus plasmid
    ORF Viral Vector vGMLP000401 Human HBB Lentivirus particle
    ORF Viral Vector vGMAP000026 Human HBB Adenovirus particle


    Target information

    Target ID GM-T31825
    Target Name HBB
    Gene ID 3043, 715559
    Gene Symbol and Synonyms beta-globin,CD113t-C,ECYT6,HBB
    Uniprot Accession P68871
    Uniprot Entry Name HBB_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Malignant neoplasm of bladder, Complications of kidney transplant, IgA glomerulonephritis
    Gene Ensembl ENSG00000244734
    Target Classification Not Available

    The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]



    About GMVC

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