Human PDZK1/CAP70/CLAMP ORF/cDNA clone-Lentivirus plasmid (NM_002614)

Cat. No.: pGMLP000679
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PDZK1/CAP70/CLAMP Lentiviral expression plasmid for PDZK1 lentivirus packaging, PDZK1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000679
Gene Name PDZK1
Accession Number NM_002614
Gene ID 5174
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1560 bp
Gene Alias CAP70,CLAMP,NHERF-3,NHERF3,PDZD1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGACCTCCACCTTCAACCCCCGAGAATGTAAACTGTCCAAGCAAGAAGGGCAAAACTATGGCTTCTTCCTGCGAATTGAGAAGGACACCGAGGGCCACCTGGTCCGGGTGGTTGAGAAGTGTAGCCCAGCAGAGAAGGCTGGCCTTCAAGATGGAGACAGAGTTCTTAGGATCAATGGTGTCTTTGTGGACAAAGAAGAACATATGCAGGTTGTGGATCTGGTCAGAAAGAGTGGGAATTCAGTGACTTTACTAGTTCTGGATGGGGATTCCTATGAGAAAGCAGTGAAAACACGGGTGGACTTGAAAGAGTTGGGTCAAAGTCAGAAGGAGCAAGGTTTGAGTGATAATATACTTTCCCCTGTGATGAATGGAGGTGTGCAAACTTGGACCCAGCCCCGGCTCTGCTATCTCGTGAAGGAAGGAGGCAGCTATGGCTTCTCTCTGAAAACTGTCCAAGGTAAAAAGGGGGTGTACATGACTGATATTACACCTCAAGGTGTGGCTATGAGAGCTGGAGTTCTGGCTGATGATCACTTGATTGAAGTGAATGGAGAGAATGTAGAGGATGCCAGCCATGAGGAAGTGGTTGAAAAGGTGAAGAAGTCAGGAAGCCGTGTCATGTTCCTGCTGGTGGACAAAGAAACTGACAAGCGTCATGTTGAGCAGAAGATACAATTCAAAAGAGAAACAGCCAGTTTGAAACTGTTACCCCACCAGCCCCGAATTGTGGAGATGAAGAAAGGAAGCAATGGCTATGGTTTCTATCTGAGGGCAGGCTCAGAACAGAAAGGTCAAATCATCAAGGACATAGATTCTGGAAGTCCAGCAGAGGAGGCTGGCTTGAAGAACAATGATCTGGTAGTTGCTGTCAACGGCGAGTCTGTGGAAACCCTGGATCATGACAGTGTGGTAGAAATGATTAGAAAGGGTGGAGATCAGACTTCACTGTTGGTGGTAGACAAAGAGACGGACAACATGTACAGACTGGCTCATTTTTCTCCATTTCTCTACTATCAAAGTCAAGAACTGCCCAATGGCTCTGTCAAGGAGGCTCCAGCTCCTACTCCCACTTCTCTGGAAGTCTCAAGTCCACCAGATACTACAGAGGAAGTAGATCATAAGCCTAAACTCTGCAGGCTGGCTAAAGGTGAAAATGGCTATGGCTTTCACTTAAATGCGATTCGGGGTCTGCCAGGCTCATTCATCAAAGAGGTACAGAAGGGCGGTCCTGCTGACTTGGCTGGGCTAGAGGATGAGGATGTCATCATTGAAGTGAATGGGGTGAATGTGCTAGATGAACCCTATGAGAAGGTGGTGGATAGAATCCAGAGCAGTGGGAAGAATGTCACACTTCTAGTCTGTGGAAAGAAGGCCTATGATTATTTCCAAGCTAAGAAAATCCCTATTGTTTCCTCCCTGGCTGATCCACTTGACACCCCTCCAGATTCTAAAGAAGGAATAGTGGTGGAGTCAAACCATGACTCGCACATGGCAAAAGAACGGGCCCACAGTACAGCCTCACATTCTTCTTCCAATTCTGAAGATACAGAGATGTGA
ORF Protein Sequence MTSTFNPRECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLVRKSGNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILSPVMNGGVQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGYGFYLRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDSVVEMIRKGGDQTSLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEVDHKPKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIPIVSSLADPLDTPPDSKEGIVVESNHDSHMAKERAHSTASHSSSNSEDTEM

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T71492-Ab Anti-PDZK1 monoclonal antibody
    Target Antigen GM-Tg-g-T71492-Ag PDZK1 protein
    ORF Viral Vector pGMLP000679 Human PDZK1 Lentivirus plasmid
    ORF Viral Vector vGMLP000679 Human PDZK1 Lentivirus particle


    Target information

    Target ID GM-T71492
    Target Name PDZK1
    Gene ID 5174, 59020, 696698, 65144, 101096825, 475823, 534439, 100065636
    Gene Symbol and Synonyms 1700023D20Rik,2610507N21Rik,4921513F16Rik,CAP70,CLAMP,D3Ertd537e,mPDZK1,naPi-Cap1,NHERF-3,NHERF3,PDZD1,PDZK1
    Uniprot Accession Q5T2W1
    Uniprot Entry Name NHRF3_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000174827
    Target Classification Not Available

    This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]



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