Human LGALS3BP/90K/BTBD17B ORF/cDNA clone-Lentivirus plasmid (NM_005567.3)

Cat. No.: pGMLP002632
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human LGALS3BP/90K/BTBD17B Lentiviral expression plasmid for LGALS3BP lentivirus packaging, LGALS3BP lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP002632
Gene Name LGALS3BP
Accession Number NM_005567.3
Gene ID 3959
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1758 bp
Gene Alias 90K,BTBD17B,CyCAP,gp90,M2BP,MAC-2-BP,TANGO10B
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGACCCCTCCGAGGCTCTTCTGGGTGTGGCTGCTGGTTGCAGGAACCCAAGGCGTGAACGATGGTGACATGCGGCTGGCCGATGGGGGCGCCACCAACCAGGGCCGCGTGGAGATCTTCTACAGAGGCCAGTGGGGCACTGTGTGTGACAACCTGTGGGACCTGACTGATGCCAGCGTCGTCTGCCGGGCCCTGGGCTTCGAGAACGCCACCCAGGCTCTGGGCAGAGCTGCCTTCGGGCAAGGATCAGGCCCCATCATGCTGGATGAGGTCCAGTGCACGGGAACCGAGGCCTCACTGGCCGACTGCAAGTCCCTGGGCTGGCTGAAGAGCAACTGCAGGCACGAGAGAGACGCTGGTGTGGTCTGCACCAATGAAACCAGGAGCACCCACACCCTGGACCTCTCCAGGGAGCTCTCGGAGGCCCTTGGCCAGATCTTTGACAGCCAGCGGGGCTGCGACCTGTCCATCAGCGTGAATGTGCAGGGCGAGGACGCCCTGGGCTTCTGTGGCCACACGGTCATCCTGACTGCCAACCTGGAGGCCCAGGCCCTGTGGAAGGAGCCGGGCAGCAATGTCACCATGAGTGTGGATGCTGAGTGTGTGCCCATGGTCAGGGACCTTCTCAGGTACTTCTACTCCCGAAGGATTGACATCACCCTGTCGTCAGTCAAGTGCTTCCACAAGCTGGCCTCTGCCTATGGGGCCAGGCAGCTGCAGGGCTACTGCGCAAGCCTCTTTGCCATCCTCCTCCCCCAGGACCCCTCGTTCCAGATGCCCCTGGACCTGTATGCCTATGCAGTGGCCACAGGGGACGCCCTGCTGGAGAAGCTCTGCCTACAGTTCCTGGCCTGGAACTTCGAGGCCTTGACGCAGGCCGAGGCCTGGCCCAGTGTCCCCACAGACCTGCTCCAACTGCTGCTGCCCAGGAGCGACCTGGCGGTGCCCAGCGAGCTGGCCCTACTGAAGGCCGTGGACACCTGGAGCTGGGGGGAGCGTGCCTCCCATGAGGAGGTGGAGGGCTTGGTGGAGAAGATCCGCTTCCCCATGATGCTCCCTGAGGAGCTCTTTGAGCTGCAGTTCAACCTGTCCCTGTACTGGAGCCACGAGGCCCTGTTCCAGAAGAAGACTCTGCAGGCCCTGGAATTCCACACTGTGCCCTTCCAGTTGCTGGCCCGGTACAAAGGCCTGAACCTCACCGAGGATACCTACAAGCCCCGGATTTACACCTCGCCCACCTGGAGTGCCTTTGTGACAGACAGTTCCTGGAGTGCACGGAAGTCACAACTGGTCTATCAGTCCAGACGGGGGCCTTTGGTCAAATATTCTTCTGATTACTTCCAAGCCCCCTCTGACTACAGATACTACCCCTACCAGTCCTTCCAGACTCCACAACACCCCAGCTTCCTCTTCCAGGACAAGAGGGTGTCCTGGTCCCTGGTCTACCTCCCCACCATCCAGAGCTGCTGGAACTACGGCTTCTCCTGCTCCTCGGACGAGCTCCCTGTCCTGGGCCTCACCAAGTCTGGCGGCTCAGATCGCACCATTGCCTACGAAAACAAAGCCCTGATGCTCTGCGAAGGGCTCTTCGTGGCAGACGTCACCGATTTCGAGGGCTGGAAGGCTGCGATTCCCAGTGCCCTGGACACCAACAGCTCGAAGAGCACCTCCTCCTTCCCCTGCCCGGCAGGGCACTTCAACGGCTTCCGCACGGTCATCCGCCCCTTCTACCTGACCAACTCCTCAGGTGTGGACTAG
ORF Protein Sequence MTPPRLFWVWLLVAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQGYCASLFAILLPQDPSFQMPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWSWGERASHEEVEGLVEKIRFPMMLPEELFELQFNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTDSSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCWNYGFSCSSDELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGWKAAIPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYLTNSSGVD

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IO086-Ab Anti-LG3BP/ LGALS3BP/ 90K functional antibody
    Target Antigen GM-Tg-g-IO086-Ag LGALS3BP protein
    ORF Viral Vector pGMLP002632 Human LGALS3BP Lentivirus plasmid
    ORF Viral Vector pGMLV001330 Human LGALS3BP Lentivirus plasmid
    ORF Viral Vector vGMLP002632 Human LGALS3BP Lentivirus particle
    ORF Viral Vector vGMLV001330 Human LGALS3BP Lentivirus particle


    Target information

    Target ID GM-IO086
    Target Name LGALS3BP
    Gene ID 3959, 19039, 710853, 245955, 531137, 100050573
    Gene Symbol and Synonyms 90K,BTBD17B,CyCAP,gp90,LGALS3BP,M2BP,MAC-2-BP,MAC-2BP,MAC2BP,mama,Ppicap,TANGO10B
    Uniprot Accession Q08380
    Uniprot Entry Name LG3BP_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Immuno-oncology Target
    Disease Ovary Cancer, Malignant neoplasm of bladder
    Gene Ensembl ENSG00000108679
    Target Classification Checkpoint-Immuno Oncology

    The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]



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