Human COX17 ORF/cDNA clone-Lentivirus plasmid (NM_005694)

Cat. No.: pGMLP002741
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human COX17/ Lentiviral expression plasmid for COX17 lentivirus packaging, COX17 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP002741
Gene Name COX17
Accession Number NM_005694
Gene ID 10063
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 192 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCCGGGTCTGGTTGACTCAAACCCTGCCCCGCCTGAGTCTCAGGAGAAGAAGCCGCTGAAGCCCTGCTGCGCTTGCCCGGAGACCAAGAAGGCGCGCGATGCGTGTATCATCGAGAAAGGAGAAGAACACTGTGGACATCTAATTGAGGCCCACAAGGAATGCATGAGAGCCCTAGGATTTAAAATATGA
ORF Protein Sequence MPGLVDSNPAPPESQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALGFKI

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T03409-Ab Anti-COX17 monoclonal antibody
    Target Antigen GM-Tg-g-T03409-Ag COX17 protein
    ORF Viral Vector pGMLP002741 Human COX17 Lentivirus plasmid
    ORF Viral Vector vGMLP002741 Human COX17 Lentivirus particle


    Target information

    Target ID GM-T03409
    Target Name COX17
    Gene ID 10063, 12856, 712917, 89786, 101080819, 503668, 100295800, 100146890
    Gene Symbol and Synonyms COX17,LOC100146890
    Uniprot Accession Q14061
    Uniprot Entry Name COX17_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000138495
    Target Classification Not Available

    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008]



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