Human NPC2/EDDM1/HE1 ORF/cDNA clone-Lentivirus plasmid (NM_006432)

Cat. No.: pGMLP002951
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human NPC2/EDDM1/HE1 Lentiviral expression plasmid for NPC2 lentivirus packaging, NPC2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP002951
Gene Name NPC2
Accession Number NM_006432
Gene ID 10577
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 456 bp
Gene Alias EDDM1,HE1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCGTTTCCTGGCAGCTACATTCCTGCTCCTGGCGCTCAGCACCGCTGCCCAGGCCGAACCGGTGCAGTTCAAGGACTGCGGTTCTGTGGATGGAGTTATAAAGGAAGTGAATGTGAGCCCATGCCCCACCCAACCCTGCCAGCTGAGCAAAGGACAGTCTTACAGCGTCAATGTCACCTTCACCAGCAATATTCAGTCTAAAAGCAGCAAGGCCGTGGTGCATGGCATCCTGATGGGCGTCCCAGTTCCCTTTCCCATTCCTGAGCCTGATGGTTGTAAGAGTGGAATTAACTGCCCTATCCAAAAAGACAAGACCTATAGCTACCTGAATAAACTACCAGTGAAAAGCGAATATCCCTCTATAAAACTGGTGGTGGAGTGGCAACTTCAGGATGACAAAAACCAAAGTCTCTTCTGCTGGGAAATCCCAGTACAGATCGTTTCTCATCTCTAA
ORF Protein Sequence MRFLAATFLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPCPTQPCQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGVPVPFPIPEPDGCKSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQIVSHL

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE1133-Ab Anti-NPC2/ EDDM1/ HE1 functional antibody
    Target Antigen GM-Tg-g-SE1133-Ag NPC2 protein
    ORF Viral Vector pGMLP002951 Human NPC2 Lentivirus plasmid
    ORF Viral Vector vGMLP002951 Human NPC2 Lentivirus particle


    Target information

    Target ID GM-SE1133
    Target Name NPC2
    Gene ID 10577, 67963, 699881, 286898, 101094270, 403920, 280815, 100051060
    Gene Symbol and Synonyms 2700012J19Rik,CE1,EDDM1,HE1,NPC2,re1
    Uniprot Accession P61916
    Uniprot Entry Name NPC2_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Ovary Cancer
    Gene Ensembl ENSG00000119655
    Target Classification Not Available

    This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008]



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