Human AGRP/AGRT/ART ORF/cDNA clone-Lentivirus plasmid (NM_001138)

Cat. No.: pGMLP003399
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human AGRP/AGRT/ART Lentiviral expression plasmid for AGRP lentivirus packaging, AGRP lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP003399
Gene Name AGRP
Accession Number NM_001138
Gene ID 181
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 399 bp
Gene Alias AGRT,ART,ASIP2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCTGACCGCAGCGGTGCTGAGCTGTGCCCTGCTGCTGGCACTGCCTGCCACGCGAGGAGCCCAGATGGGCTTGGCCCCCATGGAGGGCATCAGAAGGCCTGACCAGGCCCTGCTCCCAGAGCTCCCAGGCCTGGGCCTGCGGGCCCCACTGAAGAAGACAACTGCAGAACAGGCAGAAGAGGATCTGTTGCAGGAGGCTCAGGCCTTGGCAGAGGTACTAGACCTGCAGGACCGCGAGCCCCGCTCCTCACGTCGCTGCGTAAGGCTGCATGAGTCCTGCCTGGGACAGCAGGTGCCTTGCTGTGACCCATGTGCCACGTGCTACTGCCGCTTCTTCAATGCCTTCTGCTACTGCCGCAAGCTGGGTACTGCCATGAATCCCTGCAGCCGCACCTAG
ORF Protein Sequence MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQALLPELPGLGLRAPLKKTTAEQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T52937-Ab Anti-AGRP/ AGRT/ ART functional antibody
    Target Antigen GM-Tg-g-T52937-Ag AGRP protein
    ORF Viral Vector pGMLP003399 Human AGRP Lentivirus plasmid
    ORF Viral Vector vGMLP003399 Human AGRP Lentivirus particle


    Target information

    Target ID GM-T52937
    Target Name AGRP
    Gene ID 181, 11604, 698479, 25582, 101100855, 611198, 280987, 100066082
    Gene Symbol and Synonyms AGRP,AGRT,ART,ASIP2
    Uniprot Accession O00253
    Uniprot Entry Name AGRP_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000159723
    Target Classification Not Available

    This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]



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