Human PARL/PRO2207/PSARL ORF/cDNA clone-Lentivirus plasmid (NM_018622)

Cat. No.: pGMLP004196
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PARL/PRO2207/PSARL Lentiviral expression plasmid for PARL lentivirus packaging, PARL lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP004196
Gene Name PARL
Accession Number NM_018622
Gene ID 55486
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1140 bp
Gene Alias PRO2207,PSARL,PSARL1,PSENIP2,RHBDS1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCGTGGCGAGGCTGGGCGCAGAGAGGCTGGGGCTGCGGCCAGGCGTGGGGTGCGTCGGTGGGCGGCCGCAGCTGCGAGGAGCTCACTGCGGTCCTAACCCCGCCGCAGCTCCTCGGACGCAGGTTTAACTTCTTTATTCAACAAAAATGCGGATTCAGAAAAGCACCCAGGAAGGTTGAACCTCGAAGATCAGACCCAGGGACAAGTGGTGAAGCATACAAGAGAAGTGCTTTGATTCCTCCTGTGGAAGAAACAGTCTTTTATCCTTCTCCCTATCCTATAAGGAGTCTCATAAAACCTTTATTTTTTACTGTTGGGTTTACAGGCTGTGCATTTGGATCAGCTGCTATTTGGCAATATGAATCACTGAAATCCAGGGTCCAGAGTTATTTTGATGGTATAAAAGCTGATTGGTTGGATAGCATAAGACCACAAAAAGAAGGAGACTTCAGAAAGGAGATTAACAAGTGGTGGAATAACCTAAGTGATGGCCAGCGGACTGTGACAGGTATTATAGCTGCAAATGTCCTTGTATTCTGTTTATGGAGAGTACCTTCTCTGCAGCGGACAATGATCAGATATTTCACATCGAATCCAGCCTCAAAGGTCCTTTGTTCTCCAATGTTGCTGTCAACATTCAGTCATTTCTCCTTATTTCACATGGCAGCAAATATGTATGTTTTGTGGAGCTTCTCTTCCAGCATAGTGAACATTCTGGGTCAAGAGCAGTTCATGGCAGTGTACCTATCTGCAGGTGTTATTTCCAATTTTGTCAGTTACGTGGGTAAAGTTGCCACAGGAAGATATGGACCATCACTTGGTGCATCTGGTGCCATCATGACAGTCCTCGCAGCTGTCTGCACTAAGATCCCAGAAGGGAGGCTTGCCATTATTTTCCTTCCGATGTTCACGTTCACAGCAGGGAATGCCCTGAAAGCCATTATCGCCATGGATACAGCAGGAATGATCCTGGGATGGAAATTTTTTGATCATGCGGCACATCTTGGGGGAGCTCTTTTTGGAATATGGTATGTTACTTACGGTCATGAACTGATTTGGAAGAACAGGGAGCCGCTAGTGAAAATCTGGCATGAAATAAGGACTAATGGCCCCAAAAAAGGAGGTGGCTCTAAGTAA
ORF Protein Sequence MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP1325-Ab Anti-PARL monoclonal antibody
    Target Antigen GM-Tg-g-IP1325-Ag PARL protein
    ORF Viral Vector pGMLP004196 Human PARL Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-108 Human PARL Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-248 Human PARL Adenovirus plasmid
    ORF Viral Vector vGMLP004196 Human PARL Lentivirus particle
    ORF Viral Vector vGMLP-SPh-108 Human PARL Lentivirus particle
    ORF Viral Vector vGMAP-SPh-248 Human PARL Adenovirus particle


    Target information

    Target ID GM-IP1325
    Target Name PARL
    Gene ID 55486, 381038, 704652, 287979, 101091042, 488100, 514191, 100058851
    Gene Symbol and Synonyms D16Ertd607e,PARL,PRO2207,PSARL,PSARL1,PSENIP2,RHBDS1
    Uniprot Accession Q9H300
    Uniprot Entry Name PARL_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000175193
    Target Classification Not Available

    This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease. [provided by RefSeq, May 2016]



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