Human HTRA4 ORF/cDNA clone-Lentivirus plasmid (NM_153692)

Cat. No.: pGMLP004411
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human HTRA4/ Lentiviral expression plasmid for HTRA4 lentivirus packaging, HTRA4 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP004411
Gene Name HTRA4
Accession Number NM_153692
Gene ID 203100
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1431 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGATTAGACCTCAGCTGCGGACCGCGGGGCTGGGACGATGCCTCCTGCCGGGGCTGCTGCTGCTCCTGGTGCCCGTCCTCTGGGCCGGGGCTGAAAAGCTACATACCCAGCCCTCCTGCCCCGCGGTCTGCCAGCCCACGCGCTGCCCCGCGCTGCCCACCTGCGCGCTGGGGACCACGCCGGTGTTCGACCTGTGCCGCTGTTGCCGCGTCTGCCCCGCGGCCGAGCGTGAAGTCTGCGGCGGGGCGCAGGGCCAACCGTGCGCCCCGGGGCTGCAGTGCCTCCAGCCGCTGCGCCCCGGGTTCCCCAGCACCTGCGGTTGCCCGACGCTGGGAGGGGCCGTGTGCGGCAGCGACAGGCGCACCTACCCCAGCATGTGCGCGCTCCGGGCCGAAAACCGCGCCGCGCGCCGCCTGGGCAAGGTCCCGGCCGTGCCTGTGCAGTGGGGGAACTGCGGGGATACAGGGACCAGAAGCGCAGGCCCGCTCAGGAGGAATTACAACTTCATCGCCGCGGTGGTGGAGAAGGTGGCGCCATCGGTGGTTCACGTGCAGCTGTGGGGCAGGTTACTTCACGGCAGCAGGCTTGTTCCTGTGTACAGTGGCTCTGGGTTCATAGTGTCTGAGGACGGGCTCATTATTACCAATGCCCATGTTGTCAGGAACCAGCAGTGGATTGAGGTGGTGCTCCAGAATGGGGCCCGTTATGAAGCTGTTGTCAAGGATATTGACCTTAAATTGGATCTTGCGGTGATTAAGATTGAATCAAATGCTGAACTTCCTGTACTGATGCTGGGAAGATCATCTGACCTTCGGGCTGGAGAGTTTGTGGTGGCTTTGGGCAGCCCATTTTCTCTGCAGAACACAGCTACTGCAGGAATTGTCAGCACCAAACAGCGAGGGGGCAAAGAACTGGGGATGAAGGATTCAGATATGGACTACGTCCAGATTGATGCCACAATTAATTATGGGAATTCTGGTGGTCCTCTGGTGAACTTGGATGGTGATGTGATTGGCGTCAATTCATTGAGGGTGACTGATGGAATCTCCTTTGCAATTCCTTCAGATCGAGTTAGGCAGTTCTTGGCAGAATACCATGAGCACCAGATGAAAGGAAAGGCGTTTTCAAATAAGAAATATCTGGGTCTGCAAATGCTGTCCCTCACTGTGCCCCTTAGTGAAGAATTGAAAATGCATTATCCAGATTTCCCTGATGTGAGTTCTGGGGTTTATGTATGTAAAGTGGTTGAAGGAACAGCTGCTCAAAGCTCTGGATTGAGAGATCACGATGTAATTGTCAACATAAATGGGAAACCTATTACTACTACAACTGATGTTGTTAAAGCTCTTGACAGTGATTCCCTTTCCATGGCTGTTCTTCGGGGAAAAGATAATTTGCTCCTGACAGTCATACCTGAAACAATCAATTAA
ORF Protein Sequence MIRPQLRTAGLGRCLLPGLLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTTPVFDLCRCCRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCGCPTLGGAVCGSDRRTYPSMCALRAENRAARRLGKVPAVPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEKVAPSVVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPDVSSGVYVCKVVEGTAAQSSGLRDHDVIVNINGKPITTTTDVVKALDSDSLSMAVLRGKDNLLLTVIPETIN

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0273-Ab Anti-HTRA4 functional antibody
    Target Antigen GM-Tg-g-SE0273-Ag HTRA4 protein
    ORF Viral Vector pGMLP004411 Human HTRA4 Lentivirus plasmid
    ORF Viral Vector vGMLP004411 Human HTRA4 Lentivirus particle


    Target information

    Target ID GM-SE0273
    Target Name HTRA4
    Gene ID 203100, 330723, 700875, 306564, 101098456, 475580, 514946, 100058701
    Gene Symbol and Synonyms B430206E18Rik,HTRA4,RGD1306242
    Uniprot Accession P83105
    Uniprot Entry Name HTRA4_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000169495
    Target Classification Not Available

    This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008]



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