Human RNF6 ORF/cDNA clone-Lentivirus plasmid (NM_005977)

Cat. No.: pGMLP004424
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human RNF6/ Lentiviral expression plasmid for RNF6 lentivirus packaging, RNF6 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP004424
Gene Name RNF6
Accession Number NM_005977
Gene ID 6049
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2058 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAATCAGTCTAGATCGAGATCAGATGGTGGCAGTGAAGAAACCTTACCTCAAGACCATAATCATCATGAAAATGAGAGAAGATGGCAGCAAGAGCGTCTCCACAGAGAAGAGGCCTATTATCAGTTTATTAATGAACTCAATGATGAAGATTATCGGCTTATGAGAGACCATAATCTTTTAGGCACCCCTGGAGAAATAACATCAGAAGAACTGCAACAGCGGTTAGATGGCGTCAAGGAACAACTAGCATCTCAGCCTGACTTGAGAGATGGAACGAATTACAGAGACTCAGAAGTCCCTAGAGAAAGTTCACATGAAGATTCTCTTCTAGAATGGTTGAACACCTTTCGGCGCACAGGAAATGCAACTCGAAGTGGACAAAATGGGAACCAAACTTGGAGAGCTGTGAGTCGAACAAACCCGAACAATGGAGAGTTTCGGTTTAGTTTGGAAATCCACGTAAATCATGAAAATAGAGGATTTGAAATTCATGGAGAAGATTATACAGACATTCCACTTTCAGATAGTAACAGAGATCATACTGCAAATAGGCAACAAAGGTCAACTAGTCCTGTGGCTAGGCGAACAAGAAGCCAAACCTCAGTGAATTTCAATGGTAGTAGTTCCAACATTCCAAGGACTAGGCTTGCTTCAAGGGGGCAAAATCCAGCTGAAGGATCTTTCTCAACATTGGGAAGGTTAAGAAATGGAATTGGGGGAGCAGCTGGCATTCCTCGAGCTAACGCTTCACGCACTAATTTCAGTAGTCACACAAACCAATCAGGTGGTAGTGAACTCAGGCAAAGGGAGGGGCAACGGTTTGGAGCAGCACATGTTTGGGAAAATGGGGCTAGAAGTAATGTTACAGTGAGGAATACAAACCAAAGATTAGAGCCAATAAGATTACGATCTACTTCCAATAGTCGAAGCCGTTCACCAATTCAGAGACAGAGTGGCACTGTTTATCATAATTCCCAAAGGGAAAGTAGACCAGTACAGCAAACCACTAGAAGATCTGTTAGGAGGAGAGGTAGAACTCGAGTCTTTTTAGAGCAAGATAGAGAACGAGAACGCAGAGGTACTGCATATACCCCATTCTCTAATTCAAGGCTTGTGTCAAGAATAACAGTAGAAGAAGGAGAAGAATCCAGCAGATCCTCAACTGCTGTACGACGACATCCAACAATCACACTGGACCTTCAAGTGAGAAGGATCCGTCCTGGAGAAAATAGAGATCGGGATAGTATTGCAAATAGAACTCGATCCAGAGTAGGGCTAGCAGAAAATACAGTCACTATTGAAAGCAATAGTGGGGGCTTTCGCCGAACCATTTCTCGTTTAGAGCGGTCAGGTATTCGAACCTATGTTAGTACCATAACAGTTCCTCTTCGTAGGATTTCTGAGAATGAGCTTGTTGAGCCATCATCAGTGGCTCTTCGGTCAATTTTAAGGCAGATCATGACTGGGTTTGGAGAACTGAGTTCTCTAATGGAGGCCGATTCTGAGTCAGAACTTCAAAGAAATGGCCAGCATTTACCAGACATGCACTCAGAACTGAGTAACTTAGGTACAGATAACAACAGGAGCCAGCACAGGGAAGGTTCCTCTCAAGACAGGCAGGCCCAAGGAGACAGCACTGAAATGCATGGTGAAAACGAGACCACCCAGCCTCATACTCGAAACAGTGACAGTAGGGGTGGCAGGCAGTTGCGAAATCCAAACAATTTAGTTGAAACTGGAACACTACCCATTCTTCGCCTTGCTCACTTTTTTTTACTAAATGAAAGTGATGATGATGATCGAATACGTGGTTTAACCAAAGAGCAGATTGACAATCTTTCCACCAGGCACTATGAGCATAACAGTATTGATAGTGAACTAGGTAAAATCTGTAGTGTTTGTATTAGTGACTATGTAACTGGAAACAAGCTCAGGCAATTACCTTGCATGCATGAATTTCACATTCATTGTATTGACCGATGGCTCTCAGAGAATTGCACTTGTCCGATCTGTCGGCAGCCTGTTTTAGGGTCTAACATAGCAAACAATGGGTAA
ORF Protein Sequence MNQSRSRSDGGSEETLPQDHNHHENERRWQQERLHREEAYYQFINELNDEDYRLMRDHNLLGTPGEITSEELQQRLDGVKEQLASQPDLRDGTNYRDSEVPRESSHEDSLLEWLNTFRRTGNATRSGQNGNQTWRAVSRTNPNNGEFRFSLEIHVNHENRGFEIHGEDYTDIPLSDSNRDHTANRQQRSTSPVARRTRSQTSVNFNGSSSNIPRTRLASRGQNPAEGSFSTLGRLRNGIGGAAGIPRANASRTNFSSHTNQSGGSELRQREGQRFGAAHVWENGARSNVTVRNTNQRLEPIRLRSTSNSRSRSPIQRQSGTVYHNSQRESRPVQQTTRRSVRRRGRTRVFLEQDRERERRGTAYTPFSNSRLVSRITVEEGEESSRSSTAVRRHPTITLDLQVRRIRPGENRDRDSIANRTRSRVGLAENTVTIESNSGGFRRTISRLERSGIRTYVSTITVPLRRISENELVEPSSVALRSILRQIMTGFGELSSLMEADSESELQRNGQHLPDMHSELSNLGTDNNRSQHREGSSQDRQAQGDSTEMHGENETTQPHTRNSDSRGGRQLRNPNNLVETGTLPILRLAHFFLLNESDDDDRIRGLTKEQIDNLSTRHYEHNSIDSELGKICSVCISDYVTGNKLRQLPCMHEFHIHCIDRWLSENCTCPICRQPVLGSNIANNG

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T92105-Ab Anti-RNF6 monoclonal antibody
    Target Antigen GM-Tg-g-T92105-Ag RNF6 protein
    ORF Viral Vector pGMLP004424 Human RNF6 Lentivirus plasmid
    ORF Viral Vector pGMPC001528 Human RNF6 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP004424 Human RNF6 Lentivirus particle


    Target information

    Target ID GM-T92105
    Target Name RNF6
    Gene ID 6049, 74132, 721550, 304271, 101085851, 477332, 527056, 100050743
    Gene Symbol and Synonyms 1200013I08Rik,5730419H05Rik,RNF6
    Uniprot Accession Q9Y252
    Uniprot Entry Name RNF6_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000127870
    Target Classification Not Available

    The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008]



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