Human TRIB2/C5FW/GS3955 ORF/cDNA clone-Lentivirus plasmid (NM_021643.3)

Cat. No.: pGMLP005250
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TRIB2/C5FW/GS3955 Lentiviral expression plasmid for TRIB2 lentivirus packaging, TRIB2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP005250
Gene Name TRIB2
Accession Number NM_021643.3
Gene ID 28951
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1032 bp
Gene Alias C5FW,GS3955,TRB2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAACATACACAGGTCTACCCCCATCACAATAGCGAGATATGGGAGATCGCGGAACAAAACCCAGGATTTCGAAGAGTTGTCGTCTATAAGGTCCGCGGAGCCCAGCCAGAGTTTCAGCCCGAACCTCGGCTCCCCGAGCCCGCCCGAGACTCCGAACTTGTCGCATTGCGTTTCTTGTATCGGGAAATACTTATTGTTGGAACCTCTGGAGGGAGACCACGTTTTTCGTGCCGTGCATCTGCACAGCGGAGAGGAGCTGGTGTGCAAGGTGTTTGATATCAGCTGCTACCAGGAATCCCTGGCACCGTGCTTTTGCCTGTCTGCTCATAGTAACATCAACCAAATCACTGAAATTATCCTGGGTGAGACCAAAGCCTATGTGTTCTTTGAGCGAAGCTATGGGGACATGCATTCCTTCGTCCGCACCTGCAAGAAGCTGAGAGAGGAGGAGGCAGCCAGACTGTTCTACCAGATTGCCTCGGCAGTGGCCCACTGCCATGACGGGGGGCTGGTGCTGCGGGACCTCAAGCTGCGGAAATTCATCTTTAAGGACGAAGAGAGGACTCGGGTCAAGCTGGAAAGCCTGGAAGACGCCTACATTCTGCGGGGAGATGATGATTCCCTCTCCGACAAGCATGGCTGCCCGGCTTACGTAAGCCCAGAGATCTTGAACACCAGTGGCAGCTACTCGGGCAAAGCAGCCGACGTGTGGAGCCTGGGGGTGATGCTGTACACCATGTTGGTGGGGCGGTACCCTTTCCATGACATTGAACCCAGCTCCCTCTTCAGCAAGATCCGGCGTGGCCAGTTCAACATTCCAGAGACTCTGTCGCCCAAGGCCAAGTGCCTCATCCGAAGCATTCTGCGTCGGGAGCCCTCAGAGCGGCTGACCTCGCAGGAAATTCTGGACCATCCTTGGTTTTCTACAGATTTTAGCGTCTCGAATTCAGCATATGGTGCTAAGGAAGTGTCTGACCAGCTGGTGCCGGACGTCAACATGGAAGAGAACTTGGACCCTTTCTTTAACTGA
ORF Protein Sequence MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP2175-Ab Anti-TRIB2 monoclonal antibody
    Target Antigen GM-Tg-g-IP2175-Ag TRIB2 protein
    ORF Viral Vector pGMLP005250 Human TRIB2 Lentivirus plasmid
    ORF Viral Vector vGMLP005250 Human TRIB2 Lentivirus particle


    Target information

    Target ID GM-IP2175
    Target Name TRIB2
    Gene ID 28951, 217410, 710966, 313974, 101085367, 403884, 352960, 100056836
    Gene Symbol and Synonyms C5FW,GS3955,RGD1564451,TRB-2,TRB2,TRIB2
    Uniprot Accession Q92519
    Uniprot Entry Name TRIB2_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000071575
    Target Classification Not Available

    This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]



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