Human SH2B3/IDDM20/ LNK ORF/cDNA clone-Lentivirus plasmid (NM_005475.2)

Pre-made Human SH2B3/IDDM20/ LNK Lentiviral expression plasmid for SH2B3 lentivirus packaging, SH2B3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collectionGo to SH2B3/IDDM20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000209 Human SH2B3 Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMLV000209
Gene Name SH2B3
Accession Number NM_005475.2
Gene ID 10019
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1728 bp
Gene Alias IDDM20, LNK
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T44585-Ab Anti-SH2B3 monoclonal antibody
    Target Antigen GM-Tg-g-T44585-Ag SH2B3 protein
    ORF Viral Vector pGMLV000209 Human SH2B3 Lentivirus plasmid
    ORF Viral Vector vGMLV000209 Human SH2B3 Lentivirus particle


    Target information

    Target ID GM-T44585
    Target Name SH2B3
    Gene ID 10019, 16923, 710839, 58838, 101081760, 100683018, 614726, 100057885
    Gene Symbol and Synonyms IDDM20,LNK,SH2B3
    Uniprot Accession Q9UQQ2
    Uniprot Entry Name SH2B3_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000111252
    Target Classification Not Available

    This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.