Human RAF1/CMD1NN/ CRAF ORF/cDNA clone-Lentivirus plasmid (NM_002880.3)

Pre-made Human RAF1/CMD1NN/ CRAF Lentiviral expression plasmid for RAF1 lentivirus packaging, RAF1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collectionGo to c-RAF/RAF1/CMD1NN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000273 Human RAF1 Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug

Product Description

Catalog ID pGMLV000273
Gene Name RAF1
Accession Number NM_002880.3
Gene ID 5894
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1947 bp
Gene Alias CMD1NN, CRAF, NS5, Raf-1, c-Raf
Fluorescent Reporter mCherry
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin


    Data / case study

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    Associated products

    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T23673-Ab Anti-c-RAF monoclonal antibody
    Target Antigen GM-Tg-g-T23673-Ag c-RAF/RAF1 protein
    ORF Viral Vector pGMLV000273 Human RAF1 Lentivirus plasmid
    ORF Viral Vector pGMPC000985 Human RAF1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMAP000343 Human RAF1 Adenovirus plasmid
    ORF Viral Vector vGMLV000273 Human RAF1 Lentivirus particle
    ORF Viral Vector vGMAP000343 Human RAF1 Adenovirus particle

    Target information

    Target ID GM-T23673
    Target Name c-RAF
    Gene ID 5894, 110157, 694725, 24703, 101096047, 484648, 521196, 100051110
    Gene Symbol and Synonyms 6430402F14Rik,c-Raf,CMD1NN,CRAF,Craf1,D830050J10Rik,NS5,Raf-1,RAF1,v-Raf
    Uniprot Accession P04049
    Uniprot Entry Name RAF1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000132155
    Target Classification Kinase, Tumor-associated antigen (TAA)

    This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]

    About GMVC


    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.