Human CTSB/APPS/ CPSB ORF/cDNA clone-Lentivirus plasmid (NM_001908.4)

Pre-made Human CTSB/APPS/ CPSB Lentiviral expression plasmid for CTSB lentivirus packaging, CTSB lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000311 Human CTSB Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug

Product Description

Catalog ID pGMLV000311
Gene Name CTSB
Accession Number NM_001908.4
Gene ID 1508
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1020 bp
Fluorescent Reporter
Mammalian Cell Selection Blasticidin (BSD)
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin


    Data / case study

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    Associated products

    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T61746-Ab Anti-CATB/ CTSB/ APPS functional antibody
    Target Antigen GM-Tg-g-T61746-Ag CTSB protein
    ORF Viral Vector pGMLV000311 Human CTSB Lentivirus plasmid
    ORF Viral Vector vGMLV000311 Human CTSB Lentivirus particle

    Target information

    Target ID GM-T61746
    Target Name CTSB
    Gene ID 1508, 13030, 100424758, 64529, 101084873, 486077, 281105, 100060963
    Gene Symbol and Synonyms APPS,CATB,CB,CPSB,CTSB,KWE,RECEUP
    Uniprot Accession P07858
    Uniprot Entry Name CATB_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Malignant neoplasm of bladder, IgA glomerulonephritis, tumors
    Gene Ensembl ENSG00000164733
    Target Classification Not Available

    This gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. Both Cathepsin B and Cathepsin L are involved in the cleavage of the spike protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon its entry to the human host cell. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Sep 2020]

    About GMVC


    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.