Human TYMS/DKCD/ HST422 ORF/cDNA clone-Lentivirus plasmid (NM_001071)

Pre-made Human TYMS/DKCD/ HST422 Lentiviral expression plasmid for TYMS lentivirus packaging, TYMS lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000416 Human TYMS Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug

Product Description

Catalog ID pGMLV000416
Gene Name TYMS
Accession Number NM_001071
Gene ID 7298
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 942 bp
Gene Alias DKCD, HST422, TMS, TS
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin


    Data / case study

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    Associated products

    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T98397-Ab Anti-TYMS monoclonal antibody
    Target Antigen GM-Tg-g-T98397-Ag TYMS protein
    ORF Viral Vector pGMLV000416 Human TYMS Lentivirus plasmid
    ORF Viral Vector vGMLV000416 Human TYMS Lentivirus particle

    Target information

    Target ID GM-T98397
    Target Name TYMS
    Gene ID 7298, 22171, 697580, 29261, 101091231, 607417, 507631, 100060971
    Gene Symbol and Synonyms DKCD,HST422,TMS,TS,TYMS
    Uniprot Accession P04818
    Uniprot Entry Name TYSY_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Breast Cancer
    Gene Ensembl ENSG00000176890
    Target Classification Not Available

    Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017]

    About GMVC


    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.