Human SYVN1/DER3/HRD1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_172230.3)

Cat. No.: pGMPC000145
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SYVN1/DER3/HRD1 Non-Viral expression plasmid (overexpression vector) for mouse SYVN1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000145
Gene Name SYVN1
Accession Number NM_172230.3
Gene ID 84447
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1854 bp
Gene Alias DER3,HRD1
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin
ORF Nucleotide Sequence ATGTTCCGCACGGCAGTGATGATGGCGGCCAGCCTGGCGCTGACCGGGGCTGTGGTGGCTCACGCCTACTACCTCAAACACCAGTTCTACCCCACTGTGGTGTACCTGACCAAGTCCAGCCCCAGCATGGCAGTCCTGTACATCCAGGCCTTTGTCCTTGTCTTCCTTCTGGGCAAGGTGATGGGCAAGGTGTTCTTTGGGCAACTGAGGGCAGCAGAGATGGAGCACCTTCTGGAACGTTCCTGGTACGCCGTCACAGAGACTTGTCTGGCCTTCACCGTTTTTCGGGATGACTTCAGCCCCCGCTTTGTTGCACTCTTCACTCTTCTTCTCTTCCTCAAATGTTTCCACTGGCTGGCTGAGGACCGTGTGGACTTTATGGAACGCAGCCCCAACATCTCCTGGCTCTTTCACTGCCGCATTGTCTCTCTTATGTTCCTCCTGGGCATCCTGGACTTCCTCTTCGTCAGCCACGCCTATCACAGCATCCTGACCCGTGGGGCCTCTGTGCAGCTGGTGTTTGGCTTTGAGTATGCCATCCTGATGACGATGGTGCTCACCATCTTCATCAAGTATGTGCTGCACTCCGTGGACCTCCAGAGTGAGAACCCCTGGGACAACAAGGCTGTGTACATGCTCTACACAGAGCTGTTTACAGGCTTCATCAAGGTTCTGCTGTACATGGCCTTCATGACCATCATGATCAAGGTGCACACCTTCCCACTCTTTGCCATCCGGCCCATGTACCTGGCCATGAGACAGTTCAAGAAAGCTGTGACAGATGCCATCATGTCTCGCCGAGCCATCCGCAACATGAACACCCTGTATCCAGATGCCACCCCAGAGGAGCTCCAGGCAATGGACAATGTCTGCATCATCTGCCGAGAAGAGATGGTGACTGGTGCCAAGAGACTGCCCTGCAACCACATTTTCCATACCAGCTGCCTGCGCTCCTGGTTCCAGCGGCAGCAGACCTGCCCCACCTGCCGTATGGATGTCCTTCGTGCATCGCTGCCAGCGCAGTCACCACCACCCCCGGAGCCTGCGGATCAGGGGCCACCCCCTGCCCCCCACCCCCCACCACTCTTGCCTCAGCCCCCCAACTTCCCCCAGGGCCTCCTGCCTCCTTTTCCTCCAGGCATGTTCCCACTGTGGCCCCCCATGGGCCCCTTTCCACCTGTCCCGCCTCCCCCCAGCTCAGGAGAGGCTGTGGCTCCTCCATCCACCAGTGCAGCAGCCCTTTCTCGGCCCAGTGGAGCAGCTACAACCACAGCTGCTGGCACCAGTGCTACTGCTGCTTCTGCCACAGCATCTGGCCCAGGCTCTGGCTCTGCCCCAGAGGCTGGCCCTGCCCCTGGTTTCCCCTTCCCTCCTCCCTGGATGGGTATGCCCCTGCCTCCACCCTTTGCCTTCCCCCCAATGCCTGTGCCCCCTGCGGGCTTTGCTGGGCTGACCCCAGAGGAGCTACGAGCTCTGGAGGGCCATGAGCGGCAGCACCTGGAGGCCCGGCTGCAGAGCCTGCGTAACATCCACACACTGCTGGACGCCGCCATGCTGCAGATCAACCAGTACCTCACCGTGCTGGCCTCCTTGGGGCCCCCCCGGCCTGCCACTTCAGTCAACTCCACTGAGGAGACTGCCACTACAGTTGTTGCTGCTGCCTCCTCCACCAGCATCCCTAGCTCAGAGGCCACGACCCCAACCCCAGGAGCCTCCCCACCAGCCCCTGAAATGGAAAGGCCTCCAGCTCCTGAGTCAGTGGGCACAGAGGAGATGCCTGAGGATGGAGAGCCCGATGCAGCAGAGCTCCGCCGGCGCCGCCTGCAGAAGCTGGAGTCTCCTGTTGCCCACTGA
ORF Protein Sequence MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKVMGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPSGAATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNSTEETATTVVAAASSTSIPSSEATTPTPGASPPAPEMERPPAPESVGTEEMPEDGEPDAAELRRRRLQKLESPVAH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0155-Ab Anti-SYVN1 monoclonal antibody
    Target Antigen GM-Tg-g-IP0155-Ag SYVN1 protein
    ORF Viral Vector pGMLV002604 Human SYVN1 Lentivirus plasmid
    ORF Viral Vector pGMPC000145 Human SYVN1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV002604 Human SYVN1 Lentivirus particle


    Target information

    Target ID GM-IP0155
    Target Name SYVN1
    Gene ID 84447, 74126, 716698, 361712, 101084316, 483746, 508358, 100050962
    Gene Symbol and Synonyms 1200010C09Rik,D530017H19Rik,DER3,HRD1,RGD1310488,SYVN1
    Uniprot Accession Q86TM6
    Uniprot Entry Name SYVN1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000162298
    Target Classification Not Available

    This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011]



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