Human PKM/CTHBP/HEL-S-30 ORF/cDNA clone-Adenovirus particle (NM_002654.6)

Cat. No.: vGMAD001486

Pre-made Human PKM/CTHBP/HEL-S-30 Adenovirus for PKM overexpression in-vitro and in-vivo. The PKM adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified PKM-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD001486 Human PKM Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD001486
Gene Name PKM
Accession Number NM_002654.6
Gene ID 5315
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 1596 bp
Gene Alias CTHBP,HEL-S-30,OIP3,p58,PK3,PKM2,TCB,THBP1
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 6xHis (C-Terminal)
Promoter EF1
Resistance Kanamycin
ORF Nucleotide Sequence ATGTCGAAGCCCCATAGTGAAGCCGGGACTGCCTTCATTCAGACCCAGCAGCTGCACGCAGCCATGGCTGACACATTCCTGGAGCACATGTGCCGCCTGGACATTGATTCACCACCCATCACAGCCCGGAACACTGGCATCATCTGTACCATTGGCCCAGCTTCCCGATCAGTGGAGACGTTGAAGGAGATGATTAAGTCTGGAATGAATGTGGCTCGTCTGAACTTCTCTCATGGAACTCATGAGTACCATGCGGAGACCATCAAGAATGTGCGCACAGCCACGGAAAGCTTTGCTTCTGACCCCATCCTCTACCGGCCCGTTGCTGTGGCTCTAGACACTAAAGGACCTGAGATCCGAACTGGGCTCATCAAGGGCAGCGGCACTGCAGAGGTGGAGCTGAAGAAGGGAGCCACTCTCAAAATCACGCTGGATAACGCCTACATGGAAAAGTGTGACGAGAACATCCTGTGGCTGGACTACAAGAACATCTGCAAGGTGGTGGAAGTGGGCAGCAAGATCTACGTGGATGATGGGCTTATTTCTCTCCAGGTGAAGCAGAAAGGTGCCGACTTCCTGGTGACGGAGGTGGAAAATGGTGGCTCCTTGGGCAGCAAGAAGGGTGTGAACCTTCCTGGGGCTGCTGTGGACTTGCCTGCTGTGTCGGAGAAGGACATCCAGGATCTGAAGTTTGGGGTCGAGCAGGATGTTGATATGGTGTTTGCGTCATTCATCCGCAAGGCATCTGATGTCCATGAAGTTAGGAAGGTCCTGGGAGAGAAGGGAAAGAACATCAAGATTATCAGCAAAATCGAGAATCATGAGGGGGTTCGGAGGTTTGATGAAATCCTGGAGGCCAGTGATGGGATCATGGTGGCTCGTGGTGATCTAGGCATTGAGATTCCTGCAGAGAAGGTCTTCCTTGCTCAGAAGATGATGATTGGACGGTGCAACCGAGCTGGGAAGCCTGTCATCTGTGCTACTCAGATGCTGGAGAGCATGATCAAGAAGCCCCGCCCCACTCGGGCTGAAGGCAGTGATGTGGCCAATGCAGTCCTGGATGGAGCCGACTGCATCATGCTGTCTGGAGAAACAGCCAAAGGGGACTATCCTCTGGAGGCTGTGCGCATGCAGCACCTGATTGCCCGTGAGGCAGAGGCTGCCATCTACCACTTGCAATTATTTGAGGAACTCCGCCGCCTGGCGCCCATTACCAGCGACCCCACAGAAGCCACCGCCGTGGGTGCCGTGGAGGCCTCCTTCAAGTGCTGCAGTGGGGCCATAATCGTCCTCACCAAGTCTGGCAGGTCTGCTCACCAGGTGGCCAGATACCGCCCACGTGCCCCCATCATTGCTGTGACCCGGAATCCCCAGACAGCTCGTCAGGCCCACCTGTACCGTGGCATCTTCCCTGTGCTGTGCAAGGACCCAGTCCAGGAGGCCTGGGCTGAGGACGTGGACCTCCGGGTGAACTTTGCCATGAATGTTGGCAAGGCCCGAGGCTTCTTCAAGAAGGGAGATGTGGTCATTGTGCTGACCGGATGGCGCCCTGGCTCCGGCTTCACCAACACCATGCGTGTTGTTCCTGTGCCGTGA
ORF Protein Sequence MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T65889-Ab Anti-KPYM/ PKM/ CTHBP functional antibody
    Target Antigen GM-Tg-g-T65889-Ag PKM protein
    ORF Viral Vector pGMLP004006 Human PKM Lentivirus plasmid
    ORF Viral Vector pGMLV001018 Human PKM Lentivirus plasmid
    ORF Viral Vector pGMLV001109 Human mcherry-PKM1 Lentivirus plasmid
    ORF Viral Vector pGMLV001110 Human mCherry-PKM2 Lentivirus plasmid
    ORF Viral Vector pGMLV001112 Human eGFP-PKM1 Lentivirus plasmid
    ORF Viral Vector pGMLV001238 Human eGFP-PKM1 Lentivirus plasmid
    ORF Viral Vector pGMLV001241 Human mcherry-PKM1 Lentivirus plasmid
    ORF Viral Vector pGMLV001344 Human mCherry-PKM2 Lentivirus plasmid
    ORF Viral Vector pGMLV001345 Human eGFP-PKM2 Lentivirus plasmid
    ORF Viral Vector pGMLV001467 Human PKM Lentivirus plasmid
    ORF Viral Vector pGMLV001468 Human PKM Lentivirus plasmid
    ORF Viral Vector pGMLV001604 Human PKM Lentivirus plasmid
    ORF Viral Vector pGMLV002407 Human PKM Lentivirus plasmid
    ORF Viral Vector pGMLV002409 Human PKM Lentivirus plasmid
    ORF Viral Vector pGMAD000966 Human PKM Adenovirus plasmid
    ORF Viral Vector pGMAD001486 Human PKM Adenovirus plasmid
    ORF Viral Vector pGMPC000247 Human PKM Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000827 Human PKM Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001349 Human PKM Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001681 Human PKM Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP004006 Human PKM Lentivirus particle
    ORF Viral Vector vGMLV001018 Human PKM Lentivirus particle
    ORF Viral Vector vGMLV001109 Human mcherry-PKM1 Lentivirus particle
    ORF Viral Vector vGMLV001110 Human mCherry-PKM2 Lentivirus particle
    ORF Viral Vector vGMLV001112 Human eGFP-PKM1 Lentivirus particle
    ORF Viral Vector vGMLV001238 Human eGFP-PKM1 Lentivirus particle
    ORF Viral Vector vGMLV001241 Human mcherry-PKM1 Lentivirus particle
    ORF Viral Vector vGMLV001344 Human mCherry-PKM2 Lentivirus particle
    ORF Viral Vector vGMLV001345 Human eGFP-PKM2 Lentivirus particle
    ORF Viral Vector vGMLV001467 Human PKM Lentivirus particle
    ORF Viral Vector vGMLV001468 Human PKM Lentivirus particle
    ORF Viral Vector vGMLV001604 Human PKM Lentivirus particle
    ORF Viral Vector vGMLV002407 Human PKM Lentivirus particle
    ORF Viral Vector vGMLV002409 Human PKM Lentivirus particle
    ORF Viral Vector vGMAD000966 Human PKM Adenovirus particle
    ORF Viral Vector vGMAD001486 Human PKM Adenovirus particle


    Target information

    Target ID GM-T65889
    Target Name PKM
    Gene ID 5315, 18746, 697742, 25630, 123378905, 403874, 512571, 100063687
    Gene Symbol and Synonyms CTHBP,HEL-S-30,OIP3,p58,PK,Pk-2,Pk-3,PK3,PKM,PKM12,PKM2,TCB,THBP1
    Uniprot Accession P14618
    Uniprot Entry Name KPYM_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Congenital occlusion of ureteropelvic junction
    Gene Ensembl ENSG00000067225
    Target Classification Not Available

    This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.