Anti-INGR1/ IFNGR/ IFNGR1 monoclonal antibody

Anti-INGR1/ IFNGR/ IFNGR1 antibody for FACS & in-vivo assay

Target products collectionGo to IFNGR/IFNGR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IO066-Ab-1/ GM-Tg-hg-IO066-Ab-2Anti-Human IFNGR/IFNGR1 monoclonal antibodyHuman
GM-Tg-rg-IO066-Ab-1/ GM-Tg-rg-IO066-Ab-2Anti-Rat IFNGR/IFNGR1 monoclonal antibodyRat
GM-Tg-mg-IO066-Ab-1/ GM-Tg-mg-IO066-Ab-2Anti-Mouse IFNGR/IFNGR1 monoclonal antibodyMouse
GM-Tg-cynog-IO066-Ab-1/ GM-Tg-cynog-IO066-Ab-2Anti-Cynomolgus/ Rhesus macaque IFNGR/IFNGR1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IO066-Ab-1/ GM-Tg-felg-IO066-Ab-2Anti-Feline IFNGR/IFNGR1 monoclonal antibodyFeline
GM-Tg-cang-IO066-Ab-1/ GM-Tg-cang-IO066-Ab-2Anti-Canine IFNGR/IFNGR1 monoclonal antibodyCanine
GM-Tg-bovg-IO066-Ab-1/ GM-Tg-bovg-IO066-Ab-2Anti-Bovine IFNGR/IFNGR1 monoclonal antibodyBovine
GM-Tg-equg-IO066-Ab-1/ GM-Tg-equg-IO066-Ab-2Anti-Equine IFNGR/IFNGR1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-IO066-Ab-1/ GM-Tg-hg-IO066-Ab-2; GM-Tg-rg-IO066-Ab-1/ GM-Tg-rg-IO066-Ab-2;
GM-Tg-mg-IO066-Ab-1/ GM-Tg-mg-IO066-Ab-2; GM-Tg-cynog-IO066-Ab-1/ GM-Tg-cynog-IO066-Ab-2;
GM-Tg-felg-IO066-Ab-1/ GM-Tg-felg-IO066-Ab-2; GM-Tg-cang-IO066-Ab-1/ GM-Tg-cang-IO066-Ab-2;
GM-Tg-bovg-IO066-Ab-1/ GM-Tg-bovg-IO066-Ab-2; GM-Tg-equg-IO066-Ab-1/ GM-Tg-equg-IO066-Ab-2
Products NameAnti-IFNGR/IFNGR1 monoclonal antibody
Target NameIFNGR
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-IFNGR benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

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    Associated products

    CategoryCat No.Products Name
    BiosimilarGMP-Bios-INN-874Pre-Made Interferon Gamma Biosimilar, Recombinant Protein targeting IFNGR1: Recombinant therapeutic protein targeting CD119/IFNGR/IMD27A/IMD27B
    Target AntigenProducts DevelopingMulti-species INGR1/ IFNGR/ IFNGR1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm001350mouse Ifngr1 Lentivirus plasmid
    ORF Viral VectorvGMLPm001350mouse Ifngr1 Lentivirus particle

    Target information

    Target IDGM-IO066
    Target NameIFNGR
    Gene ID3459,15979,116465,100423877,100856077,101086811,508619,100073195
    Gene Symbol and SynonymsCD119,Ifgr,IFN-gammaR,IFNGR,IFNGR1,IFNR1,IMD27A,IMD27B,Nktar
    Uniprot AccessionP15260
    Uniprot Entry NameINGR1_HUMAN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, Immuno-oncology Target, INN Index
    Gene EnsemblENSG00000027697
    Target ClassificationCheckpoint-Immuno Oncology

    The target: IFNGR, gene name: IFNGR1, also named as CD119, IFNGR, IMD27A, IMD27B. This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.