Pre-made anti-PDE3A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.

Pre-made anti-PDE3A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PDE3A mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

The target: PDE3A, gene name: PDE3A, also named as CGI-PDE, CGI-PDE A, CGI-PDE-A, HTNB. This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].

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Catalog No.	List Price (In USD)	Discount Price (In USD)	Qty (Quantity)	Sum (In USD)
GM-Tg-hg-IP0012-Ab-1-1mg	5150	3090
GM-Tg-hg-IP0012-Ab-1-10mg	Inquiry	Inquiry
GM-Tg-hg-IP0012-Ab-1-100mg	Inquiry	Inquiry
GM-Tg-hg-IP0012-Ab-2-1mg	5150	3090
GM-Tg-hg-IP0012-Ab-2-10mg	Inquiry	Inquiry
GM-Tg-hg-IP0012-Ab-2-100mg	Inquiry	Inquiry
GM-Tg-hg-IP0012-Ab-xmg	Inquiry	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Catalog No.	GM-Tg-hg-IP0012-Ab-1, GM-Tg-hg-IP0012-Ab-2
Products Name	Anti-PDE3A monoclonal antibody
Format	mab
Target Name	PDE3A
Gene ID	PDE3A
Gene Name	PDE3A
Gene Alias	CGI-PDE, CGI-PDE A, CGI-PDE-A, HTNB
Protein Sub-location	Introcelluar Protein
Category of antibody	Therapeutics Target antibody
Derivation (species)	Mouse
Species Reactivity	Human(H)
CH1+2+3 Isotype (Receptor identification)	IgG
Type of Light Chain (VD-LC)	N/A
Expression platform	Mammalian Expression
Bioactivity validation	Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
Tag	Fc
Products description	Pre-made anti-PDE3A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity	Purity: ≥95% (SDS-PAGE)
Application	Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.