Anti-PDE3A monoclonal antibody

Pre-made anti-PDE3A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PDE3A/PDE3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0012-Ab-1/ GM-Tg-hg-IP0012-Ab-2Anti-Human PDE3A monoclonal antibodyHuman
GM-Tg-rg-IP0012-Ab-1/ GM-Tg-rg-IP0012-Ab-2Anti-Rat PDE3A monoclonal antibodyRat
GM-Tg-mg-IP0012-Ab-1/ GM-Tg-mg-IP0012-Ab-2Anti-Mouse PDE3A monoclonal antibodyMouse
GM-Tg-cynog-IP0012-Ab-1/ GM-Tg-cynog-IP0012-Ab-2Anti-Cynomolgus/ Rhesus macaque PDE3A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0012-Ab-1/ GM-Tg-felg-IP0012-Ab-2Anti-Feline PDE3A monoclonal antibodyFeline
GM-Tg-cang-IP0012-Ab-1/ GM-Tg-cang-IP0012-Ab-2Anti-Canine PDE3A monoclonal antibodyCanine
GM-Tg-bovg-IP0012-Ab-1/ GM-Tg-bovg-IP0012-Ab-2Anti-Bovine PDE3A monoclonal antibodyBovine
GM-Tg-equg-IP0012-Ab-1/ GM-Tg-equg-IP0012-Ab-2Anti-Equine PDE3A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-IP0012-Ab-1/ GM-Tg-hg-IP0012-Ab-2; GM-Tg-rg-IP0012-Ab-1/ GM-Tg-rg-IP0012-Ab-2;
GM-Tg-mg-IP0012-Ab-1/ GM-Tg-mg-IP0012-Ab-2; GM-Tg-cynog-IP0012-Ab-1/ GM-Tg-cynog-IP0012-Ab-2;
GM-Tg-felg-IP0012-Ab-1/ GM-Tg-felg-IP0012-Ab-2; GM-Tg-cang-IP0012-Ab-1/ GM-Tg-cang-IP0012-Ab-2;
GM-Tg-bovg-IP0012-Ab-1/ GM-Tg-bovg-IP0012-Ab-2; GM-Tg-equg-IP0012-Ab-1/ GM-Tg-equg-IP0012-Ab-2
Products NameAnti-PDE3A monoclonal antibody
Target NamePDE3A
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
Products descriptionPre-made anti-PDE3A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0012-Ag-1Recombinant multi-species PDE3A/ CGI-PDE/ CGI-PDE A protein

    Target information

    Target IDGM-IP0012
    Target NamePDE3A
    Gene ID5139,54611,50678,704524,610836,101088586,536636,100034086
    Gene Symbol and SynonymsA930022O17Rik,CGI-PDE,CGI-PDE A,CGI-PDE-A,HTNB,PDE3A,RNPDE3A
    Uniprot AccessionQ14432,Q62865
    Uniprot Entry NamePDE3A_HUMAN,PDE3A_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    Gene EnsemblENSG00000172572
    Target ClassificationN/A

    The target: PDE3A, gene name: PDE3A, also named as CGI-PDE, CGI-PDE A, CGI-PDE-A, HTNB. This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.