Recombinant multi-species PDE3A/ CGI-PDE/ CGI-PDE A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE3A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PDE3A, gene name: PDE3A, also named as CGI-PDE, CGI-PDE A, CGI-PDE-A, HTNB. This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-IP0012-Ag-1	Human PDE3A protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-IP0012-Ag-1	Rat PDE3A protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-IP0012-Ag-1	Mouse PDE3A protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-IP0012-Ag-1	Cynomolgus/ Rhesus macaque PDE3A protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-IP0012-Ag-1	Feline PDE3A protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-IP0012-Ag-1	Canine PDE3A protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP0012-Ag-1	Bovine PDE3A protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP0012-Ag-1	Equine PDE3A protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-IP0012-Ag, GM-Tg-rg-IP0012-Ag, GM-Tg-mg-IP0012-Ag, GM-Tg-cynog-IP0012-Ag, GM-Tg-felg-IP0012-Ag, GM-Tg-cang-IP0012-Ag, GM-Tg-bovg-IP0012-Ag, GM-Tg-equg-IP0012-Ag-1
Products Name	PDE3A protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	PDE3A
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE3A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.