Anti-MANBA/ MANB1 monoclonal antibody

Anti-MANBA/ MANB1 antibody for FACS & in-vivo assay

Target products collectionGo to MANBA/MANBA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2583-Ab-1/ GM-Tg-hg-MP2583-Ab-2Anti-Human MANBA monoclonal antibodyHuman
GM-Tg-rg-MP2583-Ab-1/ GM-Tg-rg-MP2583-Ab-2Anti-Rat MANBA monoclonal antibodyRat
GM-Tg-mg-MP2583-Ab-1/ GM-Tg-mg-MP2583-Ab-2Anti-Mouse MANBA monoclonal antibodyMouse
GM-Tg-cynog-MP2583-Ab-1/ GM-Tg-cynog-MP2583-Ab-2Anti-Cynomolgus/ Rhesus macaque MANBA monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2583-Ab-1/ GM-Tg-felg-MP2583-Ab-2Anti-Feline MANBA monoclonal antibodyFeline
GM-Tg-cang-MP2583-Ab-1/ GM-Tg-cang-MP2583-Ab-2Anti-Canine MANBA monoclonal antibodyCanine
GM-Tg-bovg-MP2583-Ab-1/ GM-Tg-bovg-MP2583-Ab-2Anti-Bovine MANBA monoclonal antibodyBovine
GM-Tg-equg-MP2583-Ab-1/ GM-Tg-equg-MP2583-Ab-2Anti-Equine MANBA monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-MP2583-Ab-1/ GM-Tg-hg-MP2583-Ab-2; GM-Tg-rg-MP2583-Ab-1/ GM-Tg-rg-MP2583-Ab-2;
GM-Tg-mg-MP2583-Ab-1/ GM-Tg-mg-MP2583-Ab-2; GM-Tg-cynog-MP2583-Ab-1/ GM-Tg-cynog-MP2583-Ab-2;
GM-Tg-felg-MP2583-Ab-1/ GM-Tg-felg-MP2583-Ab-2; GM-Tg-cang-MP2583-Ab-1/ GM-Tg-cang-MP2583-Ab-2;
GM-Tg-bovg-MP2583-Ab-1/ GM-Tg-bovg-MP2583-Ab-2; GM-Tg-equg-MP2583-Ab-1/ GM-Tg-equg-MP2583-Ab-2
Products NameAnti-MANBA monoclonal antibody
Target NameMANBA
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-MANBA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MANBA/ MANB1 VLP (virus-like particle) (Products Developing)

    Target information

    Target IDGM-MP2583
    Target NameMANBA
    Gene ID4126,110173,310864,712531,487883,101085628,281909,100067947
    Gene Symbol and Synonyms2410030O07Rik,B930014J03Rik,Bmn,MANB1,MANBA
    Uniprot AccessionO00462,Q4FZV0,Q29444
    Protein Sub-locationTransmembrane Protein
    Gene EnsemblENSG00000109323
    Target ClassificationN/A

    The target: MANBA, gene name: MANBA, also named as MANB1. This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement. [provided by RefSeq, Jul 2008].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.