Anti-ITPI2/ ITPRID2/ CS-1 monoclonal antibody

Anti-ITPI2/ ITPRID2/ CS-1 antibody for FACS & in-vivo assay

Target products collectionGo to ITPRID2/ITPRID2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2609-Ab-1/ GM-Tg-hg-MP2609-Ab-2Anti-Human ITPRID2 monoclonal antibodyHuman
GM-Tg-rg-MP2609-Ab-1/ GM-Tg-rg-MP2609-Ab-2Anti-Rat ITPRID2 monoclonal antibodyRat
GM-Tg-mg-MP2609-Ab-1/ GM-Tg-mg-MP2609-Ab-2Anti-Mouse ITPRID2 monoclonal antibodyMouse
GM-Tg-cynog-MP2609-Ab-1/ GM-Tg-cynog-MP2609-Ab-2Anti-Cynomolgus/ Rhesus macaque ITPRID2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2609-Ab-1/ GM-Tg-felg-MP2609-Ab-2Anti-Feline ITPRID2 monoclonal antibodyFeline
GM-Tg-cang-MP2609-Ab-1/ GM-Tg-cang-MP2609-Ab-2Anti-Canine ITPRID2 monoclonal antibodyCanine
GM-Tg-bovg-MP2609-Ab-1/ GM-Tg-bovg-MP2609-Ab-2Anti-Bovine ITPRID2 monoclonal antibodyBovine
GM-Tg-equg-MP2609-Ab-1/ GM-Tg-equg-MP2609-Ab-2Anti-Equine ITPRID2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2609-Ab-1/ GM-Tg-hg-MP2609-Ab-2; GM-Tg-rg-MP2609-Ab-1/ GM-Tg-rg-MP2609-Ab-2;
GM-Tg-mg-MP2609-Ab-1/ GM-Tg-mg-MP2609-Ab-2; GM-Tg-cynog-MP2609-Ab-1/ GM-Tg-cynog-MP2609-Ab-2;
GM-Tg-felg-MP2609-Ab-1/ GM-Tg-felg-MP2609-Ab-2; GM-Tg-cang-MP2609-Ab-1/ GM-Tg-cang-MP2609-Ab-2;
GM-Tg-bovg-MP2609-Ab-1/ GM-Tg-bovg-MP2609-Ab-2; GM-Tg-equg-MP2609-Ab-1/ GM-Tg-equg-MP2609-Ab-2
Products NameAnti-ITPRID2 monoclonal antibody
Formatmab
Target NameITPRID2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ITPRID2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ITPI2/ ITPRID2/ CS-1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2609
    Target NameITPRID2
    Gene ID6744,70599,311146,705181,478824,101082254,538826,100053992
    Gene Symbol and Synonyms5730488C15Rik,CS-1,CS1,ITPRID2,KRAP,mKIAA1927,SPAG13,SSFA2
    Uniprot AccessionP28290
    Uniprot Entry NameITPI2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000138434
    Target ClassificationN/A

    The target: ITPRID2, gene name: ITPRID2, also named as CS-1, CS1, KRAP, SPAG13, SSFA2. Enables actin filament binding activity. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.