Anti-REL3/ RLN3/ H3 functional antibody

Anti-REL3/ RLN3/ H3 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to RLN3/RLN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1243-Ab-1/ GM-Tg-hg-SE1243-Ab-2Anti-Human RLN3 monoclonal antibodyHuman
GM-Tg-rg-SE1243-Ab-1/ GM-Tg-rg-SE1243-Ab-2Anti-Rat RLN3 monoclonal antibodyRat
GM-Tg-mg-SE1243-Ab-1/ GM-Tg-mg-SE1243-Ab-2Anti-Mouse RLN3 monoclonal antibodyMouse
GM-Tg-cynog-SE1243-Ab-1/ GM-Tg-cynog-SE1243-Ab-2Anti-Cynomolgus/ Rhesus macaque RLN3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1243-Ab-1/ GM-Tg-felg-SE1243-Ab-2Anti-Feline RLN3 monoclonal antibodyFeline
GM-Tg-cang-SE1243-Ab-1/ GM-Tg-cang-SE1243-Ab-2Anti-Canine RLN3 monoclonal antibodyCanine
GM-Tg-bovg-SE1243-Ab-1/ GM-Tg-bovg-SE1243-Ab-2Anti-Bovine RLN3 monoclonal antibodyBovine
GM-Tg-equg-SE1243-Ab-1/ GM-Tg-equg-SE1243-Ab-2Anti-Equine RLN3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-SE1243-Ab-1/ GM-Tg-hg-SE1243-Ab-2; GM-Tg-rg-SE1243-Ab-1/ GM-Tg-rg-SE1243-Ab-2;
GM-Tg-mg-SE1243-Ab-1/ GM-Tg-mg-SE1243-Ab-2; GM-Tg-cynog-SE1243-Ab-1/ GM-Tg-cynog-SE1243-Ab-2;
GM-Tg-felg-SE1243-Ab-1/ GM-Tg-felg-SE1243-Ab-2; GM-Tg-cang-SE1243-Ab-1/ GM-Tg-cang-SE1243-Ab-2;
GM-Tg-bovg-SE1243-Ab-1/ GM-Tg-bovg-SE1243-Ab-2; GM-Tg-equg-SE1243-Ab-1/ GM-Tg-equg-SE1243-Ab-2
Products NameAnti-RLN3 monoclonal antibody
Target NameRLN3
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-RLN3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1243-Ag-1Recombinant multi-species REL3/ RLN3/ H3 protein
    ORF Viral VectorpGMLP005057human RLN3 Lentivirus plasmid
    ORF Viral VectorvGMLP005057human RLN3 Lentivirus particle
    ORF Viral VectorpGMLPm003515mouse Rln3 Lentivirus plasmid
    ORF Viral VectorvGMLPm003515mouse Rln3 Lentivirus particle

    Target information

    Target IDGM-SE1243
    Target NameRLN3
    Gene ID117579,212108,266997,717577,119864730,101090240,100300034,100630151
    Gene Symbol and SynonymsH3,insl7,M3,RLN3,RLX3,RXN3,ZINS4
    Uniprot AccessionQ8WXF3,Q8BFS3
    Uniprot Entry NameREL3_HUMAN,REL3_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Gene EnsemblENSG00000171136
    Target ClassificationN/A

    The target: RLN3, gene name: RLN3, also named as H3, RXN3, ZINS4, insl7. This gene encodes a member of the relaxin family of insulin-like hormones that is expressed predominantly in the brain and plays a role in physiological processes such as stress, memory and appetite regulation. The encoded protein is a precursor that is proteolytically processed to generate a heterodimeric mature form consisting A and B chains interlinked by disulfide bonds. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.