Anti-ECP/ RNASE3/ RAF1 functional antibody

Anti-ECP/ RNASE3/ RAF1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to RNASE3/RNASE3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1248-Ab-1/ GM-Tg-hg-SE1248-Ab-2Anti-Human RNASE3 monoclonal antibodyHuman
GM-Tg-rg-SE1248-Ab-1/ GM-Tg-rg-SE1248-Ab-2Anti-Rat RNASE3 monoclonal antibodyRat
GM-Tg-mg-SE1248-Ab-1/ GM-Tg-mg-SE1248-Ab-2Anti-Mouse RNASE3 monoclonal antibodyMouse
GM-Tg-cynog-SE1248-Ab-1/ GM-Tg-cynog-SE1248-Ab-2Anti-Cynomolgus/ Rhesus macaque RNASE3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1248-Ab-1/ GM-Tg-felg-SE1248-Ab-2Anti-Feline RNASE3 monoclonal antibodyFeline
GM-Tg-cang-SE1248-Ab-1/ GM-Tg-cang-SE1248-Ab-2Anti-Canine RNASE3 monoclonal antibodyCanine
GM-Tg-bovg-SE1248-Ab-1/ GM-Tg-bovg-SE1248-Ab-2Anti-Bovine RNASE3 monoclonal antibodyBovine
GM-Tg-equg-SE1248-Ab-1/ GM-Tg-equg-SE1248-Ab-2Anti-Equine RNASE3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-SE1248-Ab-1/ GM-Tg-hg-SE1248-Ab-2; GM-Tg-rg-SE1248-Ab-1/ GM-Tg-rg-SE1248-Ab-2;
GM-Tg-mg-SE1248-Ab-1/ GM-Tg-mg-SE1248-Ab-2; GM-Tg-cynog-SE1248-Ab-1/ GM-Tg-cynog-SE1248-Ab-2;
GM-Tg-felg-SE1248-Ab-1/ GM-Tg-felg-SE1248-Ab-2; GM-Tg-cang-SE1248-Ab-1/ GM-Tg-cang-SE1248-Ab-2;
GM-Tg-bovg-SE1248-Ab-1/ GM-Tg-bovg-SE1248-Ab-2; GM-Tg-equg-SE1248-Ab-1/ GM-Tg-equg-SE1248-Ab-2
Products NameAnti-RNASE3 monoclonal antibody
Target NameRNASE3
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-RNASE3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1248-Ag-1Recombinant multi-species ECP/ RNASE3/ RAF1 protein
    ORF Viral VectorvGMLP004675human RNS3 Lentivirus particle
    ORF Viral VectorpGMLP004675human RNS3 Lentivirus plasmid

    Target information

    Target IDGM-SE1248
    Target NameRNASE3
    Gene ID6037
    Gene Symbol and SynonymsECP,RAF1,RNASE3,RNS3
    Uniprot AccessionP12724
    Uniprot Entry NameECP_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Gene EnsemblENSG00000169397
    Target ClassificationN/A

    The target: RNASE3, gene name: RNASE3, also named as ECP, RAF1, RNS3. The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein exhibits antimicrobial activity against pathogenic bacteria [provided by RefSeq, Oct 2014].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.