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Anti-RNT2/ RNASET2/ RNASE6PL functional antibody
Anti-RNT2/ RNASET2/ RNASE6PL functional antibody for cell culture, ELISA & in-vivo assay
Go to RNASET2/RNASET2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
SDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1251-Ab-1/ GM-Tg-hg-SE1251-Ab-2 | Anti-Human RNASET2 monoclonal antibody | Human |
| GM-Tg-rg-SE1251-Ab-1/ GM-Tg-rg-SE1251-Ab-2 | Anti-Rat RNASET2 monoclonal antibody | Rat |
| GM-Tg-mg-SE1251-Ab-1/ GM-Tg-mg-SE1251-Ab-2 | Anti-Mouse RNASET2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1251-Ab-1/ GM-Tg-cynog-SE1251-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RNASET2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1251-Ab-1/ GM-Tg-felg-SE1251-Ab-2 | Anti-Feline RNASET2 monoclonal antibody | Feline |
| GM-Tg-cang-SE1251-Ab-1/ GM-Tg-cang-SE1251-Ab-2 | Anti-Canine RNASET2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1251-Ab-1/ GM-Tg-bovg-SE1251-Ab-2 | Anti-Bovine RNASET2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1251-Ab-1/ GM-Tg-equg-SE1251-Ab-2 | Anti-Equine RNASET2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1251-Ab-1/ GM-Tg-hg-SE1251-Ab-2; GM-Tg-rg-SE1251-Ab-1/ GM-Tg-rg-SE1251-Ab-2; GM-Tg-mg-SE1251-Ab-1/ GM-Tg-mg-SE1251-Ab-2; GM-Tg-cynog-SE1251-Ab-1/ GM-Tg-cynog-SE1251-Ab-2; GM-Tg-felg-SE1251-Ab-1/ GM-Tg-felg-SE1251-Ab-2; GM-Tg-cang-SE1251-Ab-1/ GM-Tg-cang-SE1251-Ab-2; GM-Tg-bovg-SE1251-Ab-1/ GM-Tg-bovg-SE1251-Ab-2; GM-Tg-equg-SE1251-Ab-1/ GM-Tg-equg-SE1251-Ab-2 |
| Products Name | Anti-RNASET2 monoclonal antibody |
| Format | mab |
| Target Name | RNASET2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RNASET2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1251-Ag-1 | Recombinant multi-species RNT2/ RNASET2/ RNASE6PL protein |
| ORF Viral Vector | vGMLP002180 | human RNASET2 Lentivirus particle |
| ORF Viral Vector | pGMLP002180 | human RNASET2 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002262 | mouse Rnaset2a Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002262 | mouse Rnaset2a Lentivirus particle |
Target information
| Target ID | GM-SE1251 |
| Target Name | RNASET2 |
| Gene ID | 8635,100037283,292306,706533,612451,101080386,508245,100055381 |
| Gene Symbol and Synonyms | 0610007O07Rik,4833423A10Rik,4930532K22Rik,bA514O12.3,RNASE6PL,RNASET2,Rnaset2a |
| Uniprot Accession | O00584 |
| Uniprot Entry Name | RNT2_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000026297 |
| Target Classification | N/A |
The target: RNASET2, gene name: RNASET2, also named as RNASE6PL, bA514O12.3. This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s TaurusTM and LIBRATM platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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