Anti-RNT2/ RNASET2/ RNASE6PL functional antibody

Anti-RNT2/ RNASET2/ RNASE6PL functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to RNASET2/RNASET2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1251-Ab-1/ GM-Tg-hg-SE1251-Ab-2Anti-Human RNASET2 monoclonal antibodyHuman
GM-Tg-rg-SE1251-Ab-1/ GM-Tg-rg-SE1251-Ab-2Anti-Rat RNASET2 monoclonal antibodyRat
GM-Tg-mg-SE1251-Ab-1/ GM-Tg-mg-SE1251-Ab-2Anti-Mouse RNASET2 monoclonal antibodyMouse
GM-Tg-cynog-SE1251-Ab-1/ GM-Tg-cynog-SE1251-Ab-2Anti-Cynomolgus/ Rhesus macaque RNASET2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1251-Ab-1/ GM-Tg-felg-SE1251-Ab-2Anti-Feline RNASET2 monoclonal antibodyFeline
GM-Tg-cang-SE1251-Ab-1/ GM-Tg-cang-SE1251-Ab-2Anti-Canine RNASET2 monoclonal antibodyCanine
GM-Tg-bovg-SE1251-Ab-1/ GM-Tg-bovg-SE1251-Ab-2Anti-Bovine RNASET2 monoclonal antibodyBovine
GM-Tg-equg-SE1251-Ab-1/ GM-Tg-equg-SE1251-Ab-2Anti-Equine RNASET2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-SE1251-Ab-1/ GM-Tg-hg-SE1251-Ab-2; GM-Tg-rg-SE1251-Ab-1/ GM-Tg-rg-SE1251-Ab-2;
GM-Tg-mg-SE1251-Ab-1/ GM-Tg-mg-SE1251-Ab-2; GM-Tg-cynog-SE1251-Ab-1/ GM-Tg-cynog-SE1251-Ab-2;
GM-Tg-felg-SE1251-Ab-1/ GM-Tg-felg-SE1251-Ab-2; GM-Tg-cang-SE1251-Ab-1/ GM-Tg-cang-SE1251-Ab-2;
GM-Tg-bovg-SE1251-Ab-1/ GM-Tg-bovg-SE1251-Ab-2; GM-Tg-equg-SE1251-Ab-1/ GM-Tg-equg-SE1251-Ab-2
Products NameAnti-RNASET2 monoclonal antibody
Target NameRNASET2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-RNASET2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

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    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1251-Ag-1Recombinant multi-species RNT2/ RNASET2/ RNASE6PL protein
    ORF Viral VectorvGMLP002180human RNASET2 Lentivirus particle
    ORF Viral VectorpGMLP002180human RNASET2 Lentivirus plasmid
    ORF Viral VectorpGMLPm002262mouse Rnaset2a Lentivirus plasmid
    ORF Viral VectorvGMLPm002262mouse Rnaset2a Lentivirus particle

    Target information

    Target IDGM-SE1251
    Target NameRNASET2
    Gene ID8635,100037283,292306,706533,612451,101080386,508245,100055381
    Gene Symbol and Synonyms0610007O07Rik,4833423A10Rik,4930532K22Rik,bA514O12.3,RNASE6PL,RNASET2,Rnaset2a
    Uniprot AccessionO00584
    Uniprot Entry NameRNT2_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Gene EnsemblENSG00000026297
    Target ClassificationN/A

    The target: RNASET2, gene name: RNASET2, also named as RNASE6PL, bA514O12.3. This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008].

    About Gmab

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s TaurusTM and LIBRATM platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.