Anti-WNT8B functional antibody

Anti-WNT8B functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to WNT8B/WNT8B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1385-Ab-1/ GM-Tg-hg-SE1385-Ab-2Anti-Human WNT8B monoclonal antibodyHuman
GM-Tg-rg-SE1385-Ab-1/ GM-Tg-rg-SE1385-Ab-2Anti-Rat WNT8B monoclonal antibodyRat
GM-Tg-mg-SE1385-Ab-1/ GM-Tg-mg-SE1385-Ab-2Anti-Mouse WNT8B monoclonal antibodyMouse
GM-Tg-cynog-SE1385-Ab-1/ GM-Tg-cynog-SE1385-Ab-2Anti-Cynomolgus/ Rhesus macaque WNT8B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1385-Ab-1/ GM-Tg-felg-SE1385-Ab-2Anti-Feline WNT8B monoclonal antibodyFeline
GM-Tg-cang-SE1385-Ab-1/ GM-Tg-cang-SE1385-Ab-2Anti-Canine WNT8B monoclonal antibodyCanine
GM-Tg-bovg-SE1385-Ab-1/ GM-Tg-bovg-SE1385-Ab-2Anti-Bovine WNT8B monoclonal antibodyBovine
GM-Tg-equg-SE1385-Ab-1/ GM-Tg-equg-SE1385-Ab-2Anti-Equine WNT8B monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-SE1385-Ab-1/ GM-Tg-hg-SE1385-Ab-2; GM-Tg-rg-SE1385-Ab-1/ GM-Tg-rg-SE1385-Ab-2;
GM-Tg-mg-SE1385-Ab-1/ GM-Tg-mg-SE1385-Ab-2; GM-Tg-cynog-SE1385-Ab-1/ GM-Tg-cynog-SE1385-Ab-2;
GM-Tg-felg-SE1385-Ab-1/ GM-Tg-felg-SE1385-Ab-2; GM-Tg-cang-SE1385-Ab-1/ GM-Tg-cang-SE1385-Ab-2;
GM-Tg-bovg-SE1385-Ab-1/ GM-Tg-bovg-SE1385-Ab-2; GM-Tg-equg-SE1385-Ab-1/ GM-Tg-equg-SE1385-Ab-2
Products NameAnti-WNT8B monoclonal antibody
Target NameWNT8B
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-WNT8B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1385-Ag-1Recombinant multi-species WNT8B protein
    CytokineGM-Tg-g-SE1385-Ag-1wingless-type MMTV integration site family, member 8B (WNT8B) protein

    Target information

    Target IDGM-SE1385
    Target NameWNT8B
    Gene ID7479,22423,293990,710242,486841,101096357,538720,100070360
    Gene Symbol and SynonymsWNT8B
    Uniprot AccessionQ93098
    Uniprot Entry NameWNT8B_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    Gene EnsemblENSG00000075290
    Target ClassificationN/A

    The target: WNT8B, gene name: WNT8B, also named as . The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy..

    About Gmab

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s TaurusTM and LIBRATM platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.