Anti-ICAM1/ BB2/ CD54 monoclonal antibody

Anti-ICAM1/ BB2/ CD54 antibody for FACS & in-vivo assay

Target products collectionGo to ICAM1/ICAM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T26203-Ab-1/ GM-Tg-hg-T26203-Ab-2Anti-Human ICAM1 monoclonal antibodyHuman
GM-Tg-rg-T26203-Ab-1/ GM-Tg-rg-T26203-Ab-2Anti-Rat ICAM1 monoclonal antibodyRat
GM-Tg-mg-T26203-Ab-1/ GM-Tg-mg-T26203-Ab-2Anti-Mouse ICAM1 monoclonal antibodyMouse
GM-Tg-cynog-T26203-Ab-1/ GM-Tg-cynog-T26203-Ab-2Anti-Cynomolgus/ Rhesus macaque ICAM1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T26203-Ab-1/ GM-Tg-felg-T26203-Ab-2Anti-Feline ICAM1 monoclonal antibodyFeline
GM-Tg-cang-T26203-Ab-1/ GM-Tg-cang-T26203-Ab-2Anti-Canine ICAM1 monoclonal antibodyCanine
GM-Tg-bovg-T26203-Ab-1/ GM-Tg-bovg-T26203-Ab-2Anti-Bovine ICAM1 monoclonal antibodyBovine
GM-Tg-equg-T26203-Ab-1/ GM-Tg-equg-T26203-Ab-2Anti-Equine ICAM1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T26203-Ab-1/ GM-Tg-hg-T26203-Ab-2; GM-Tg-rg-T26203-Ab-1/ GM-Tg-rg-T26203-Ab-2;
GM-Tg-mg-T26203-Ab-1/ GM-Tg-mg-T26203-Ab-2; GM-Tg-cynog-T26203-Ab-1/ GM-Tg-cynog-T26203-Ab-2;
GM-Tg-felg-T26203-Ab-1/ GM-Tg-felg-T26203-Ab-2; GM-Tg-cang-T26203-Ab-1/ GM-Tg-cang-T26203-Ab-2;
GM-Tg-bovg-T26203-Ab-1/ GM-Tg-bovg-T26203-Ab-2; GM-Tg-equg-T26203-Ab-1/ GM-Tg-equg-T26203-Ab-2
Products NameAnti-ICAM1 monoclonal antibody
Target NameICAM1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
Products descriptionPre-made anti-ICAM1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

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    Associated products

    CategoryCat No.Products Name
    BiosimilarGMP-Bios-INN-834Pre-Made Enlimomab Biosimilar, Whole Mab, Anti-ICAM1 Antibody: Anti-BB2/CD54/P3.58 therapeutic antibody
    BiosimilarGMP-Bios-ab-064Pre-Made Bersanlimab biosimilar, Whole mAb, Anti-ICAM1 Antibody: Anti-BB2/CD54/P3.58 therapeutic antibody
    Target AntigenProducts DevelopingMulti-species ICAM1/ BB2/ CD54 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMAP000135Human ICAM1 Adenovirus plasmid
    ORF Viral VectorvGMAP000135Human ICAM1 Adenovirus particle
    ORF Viral VectorpGMAAV000306house mouse Icam1 AAV plasmid
    ORF Viral VectorvGMAAV000306house mouse Icam1 AAV particle

    Target information

    Target IDGM-T26203
    Target NameICAM1
    Gene ID3383,15894,712280,403975,101089421,100058207
    Gene Symbol and SynonymsBB2,CD54,Icam-1,ICAM1,Ly-47,MALA-2,P3.58
    Uniprot AccessionP05362,Q5NKV6,P33729
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, Immuno-oncology Target, INN Index
    DiseasePancreas Cancer, asthma, Inflammation, Thrombosis, Chronic Kidney Disease, Kidney transplant rejection, Lupus Glomerulonephritis, Systemic lupus erythematosus (SLE), breast cancer
    Gene EnsemblENSG00000090339
    Target ClassificationCheckpoint-Immuno Oncology

    The target: ICAM1, gene name: ICAM1, also named as BB2, CD54, P3.58. This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.