ICAM1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of ICAM1. The page also collects GeneMedi's different modalities and formats products for ICAM1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ICAM1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]
|Gene Official Name||ICAM1|
|Gene Alias||BB2, CD54, P3.58|
|Protein Sub-location||Transmembrane Protein|
|Category||Therapeutics Target, INN Index, Immuno-oncology Target|
Pre-made ICAM1-specific INN-index biosimilar (antibody&conjugates)-enlimomab pegol, enlimomab, Bersanlimab
Anti-ICAM1 therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
|Cat No.||Products Name (INN Index)||INN Name||Previous Name||Target||Format||Order|
|GMP-Bios-INN-834||Pre-Made Enlimomab Biosimilar, Whole Mab, Anti-ICAM1 Antibody: Anti-BB2/CD54/P3.58 therapeutic antibody||enlimomab||ICAM1||Whole mAb|
|GMP-Bios-ab-064||Pre-Made Bersanlimab biosimilar, Whole mAb, Anti-ICAM1 Antibody: Anti-BB2/CD54/P3.58 therapeutic antibody||Bersanlimab||ICAM1||Whole mAb|
Pre-made anti-ICAM1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-ICAM1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ICAM1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
|Cat No.||Antibody Name||Format||Classified by tag||Order|
|GM-Tg-hg-T26203-Ab||Anti-ICAM1 monoclonal antibody||mab||Biofunctional antibody, Therapeutics Target antibody|