- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-CNR2/ CB2/ CB-2 monoclonal antibody
Anti-CNR2/ CB2/ CB-2 antibody for FACS & in-vivo assay
Go to CB2/CNR2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T37693-Ab-1/ GM-Tg-hg-T37693-Ab-2 | Anti-Human CB2/CNR2 monoclonal antibody | Human |
| GM-Tg-rg-T37693-Ab-1/ GM-Tg-rg-T37693-Ab-2 | Anti-Rat CB2/CNR2 monoclonal antibody | Rat |
| GM-Tg-mg-T37693-Ab-1/ GM-Tg-mg-T37693-Ab-2 | Anti-Mouse CB2/CNR2 monoclonal antibody | Mouse |
| GM-Tg-cynog-T37693-Ab-1/ GM-Tg-cynog-T37693-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CB2/CNR2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T37693-Ab-1/ GM-Tg-felg-T37693-Ab-2 | Anti-Feline CB2/CNR2 monoclonal antibody | Feline |
| GM-Tg-cang-T37693-Ab-1/ GM-Tg-cang-T37693-Ab-2 | Anti-Canine CB2/CNR2 monoclonal antibody | Canine |
| GM-Tg-bovg-T37693-Ab-1/ GM-Tg-bovg-T37693-Ab-2 | Anti-Bovine CB2/CNR2 monoclonal antibody | Bovine |
| GM-Tg-equg-T37693-Ab-1/ GM-Tg-equg-T37693-Ab-2 | Anti-Equine CB2/CNR2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T37693-Ab-1/ GM-Tg-hg-T37693-Ab-2; GM-Tg-rg-T37693-Ab-1/ GM-Tg-rg-T37693-Ab-2; GM-Tg-mg-T37693-Ab-1/ GM-Tg-mg-T37693-Ab-2; GM-Tg-cynog-T37693-Ab-1/ GM-Tg-cynog-T37693-Ab-2; GM-Tg-felg-T37693-Ab-1/ GM-Tg-felg-T37693-Ab-2; GM-Tg-cang-T37693-Ab-1/ GM-Tg-cang-T37693-Ab-2; GM-Tg-bovg-T37693-Ab-1/ GM-Tg-bovg-T37693-Ab-2; GM-Tg-equg-T37693-Ab-1/ GM-Tg-equg-T37693-Ab-2 |
| Products Name | Anti-CB2/CNR2 monoclonal antibody |
| Format | mab |
| Target Name | CB2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CB2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CNR2/ CB2/ CB-2 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003590 | human CNR2 Lentivirus particle |
| ORF Viral Vector | pGMLP003590 | human CNR2 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000242 | house mouse Cnr2 AAV plasmid |
| ORF Viral Vector | pGMLPm001962 | mouse Cnr2 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm005447 | mouse Cnr2 Lentivirus plasmid |
| ORF Viral Vector | vGMAAV000242 | house mouse Cnr2 AAV particle |
| ORF Viral Vector | vGMLPm001962 | mouse Cnr2 Lentivirus particle |
| ORF Viral Vector | vGMLPm005447 | mouse Cnr2 Lentivirus particle |
Target information
| Target ID | GM-T37693 |
| Target Name | CB2 |
| Gene ID | 1269,12802,57302,711155,612289,101100234,539769,100071536 |
| Gene Symbol and Synonyms | CB-2,CB2,CB2-R,CB2C,CNR2,CNR2C,CX5 |
| Uniprot Accession | P34972,Q9QZN9 |
| Uniprot Entry Name | CNR2_HUMAN,CNR2_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000188822 |
| Target Classification | Checkpoint-Immuno Oncology, GPCR |
The target: CB2, gene name: CNR2, also named as CB-2, CB2, CX5. The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
