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Anti-ADH1A/ ADH1 monoclonal antibody
Anti-ADH1A/ ADH1 antibody for FACS & in-vivo assay
Go to ADH1A/ADH1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T65570-Ab-1/ GM-Tg-hg-T65570-Ab-2 | Anti-Human ADH1A monoclonal antibody | Human |
| GM-Tg-rg-T65570-Ab-1/ GM-Tg-rg-T65570-Ab-2 | Anti-Rat ADH1A monoclonal antibody | Rat |
| GM-Tg-mg-T65570-Ab-1/ GM-Tg-mg-T65570-Ab-2 | Anti-Mouse ADH1A monoclonal antibody | Mouse |
| GM-Tg-cynog-T65570-Ab-1/ GM-Tg-cynog-T65570-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ADH1A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T65570-Ab-1/ GM-Tg-felg-T65570-Ab-2 | Anti-Feline ADH1A monoclonal antibody | Feline |
| GM-Tg-cang-T65570-Ab-1/ GM-Tg-cang-T65570-Ab-2 | Anti-Canine ADH1A monoclonal antibody | Canine |
| GM-Tg-bovg-T65570-Ab-1/ GM-Tg-bovg-T65570-Ab-2 | Anti-Bovine ADH1A monoclonal antibody | Bovine |
| GM-Tg-equg-T65570-Ab-1/ GM-Tg-equg-T65570-Ab-2 | Anti-Equine ADH1A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T65570-Ab-1/ GM-Tg-hg-T65570-Ab-2; GM-Tg-rg-T65570-Ab-1/ GM-Tg-rg-T65570-Ab-2; GM-Tg-mg-T65570-Ab-1/ GM-Tg-mg-T65570-Ab-2; GM-Tg-cynog-T65570-Ab-1/ GM-Tg-cynog-T65570-Ab-2; GM-Tg-felg-T65570-Ab-1/ GM-Tg-felg-T65570-Ab-2; GM-Tg-cang-T65570-Ab-1/ GM-Tg-cang-T65570-Ab-2; GM-Tg-bovg-T65570-Ab-1/ GM-Tg-bovg-T65570-Ab-2; GM-Tg-equg-T65570-Ab-1/ GM-Tg-equg-T65570-Ab-2 |
| Products Name | Anti-ADH1A monoclonal antibody |
| Format | mab |
| Target Name | ADH1A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ADH1A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ADH1A/ ADH1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP002303 | human ADH1A Lentivirus plasmid |
| ORF Viral Vector | vGMLP002303 | human ADH1A Lentivirus particle |
Target information
| Target ID | GM-T65570 |
| Target Name | ADH1A |
| Gene ID | 124 |
| Gene Symbol and Synonyms | ADH1,ADH1A |
| Uniprot Accession | P07327 |
| Uniprot Entry Name | ADH1A_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000187758 |
| Target Classification | N/A |
The target: ADH1A, gene name: ADH1A, also named as ADH1. This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence. [provided by RefSeq, Nov 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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