Anti-IDO1 monoclonal antibody

Pre-made anti-IDO1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to IDO1/IDO1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T89697-Ab-1/ GM-Tg-hg-T89697-Ab-2Anti-Human IDO1 monoclonal antibodyHuman
GM-Tg-rg-T89697-Ab-1/ GM-Tg-rg-T89697-Ab-2Anti-Rat IDO1 monoclonal antibodyRat
GM-Tg-mg-T89697-Ab-1/ GM-Tg-mg-T89697-Ab-2Anti-Mouse IDO1 monoclonal antibodyMouse
GM-Tg-cynog-T89697-Ab-1/ GM-Tg-cynog-T89697-Ab-2Anti-Cynomolgus/ Rhesus macaque IDO1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T89697-Ab-1/ GM-Tg-felg-T89697-Ab-2Anti-Feline IDO1 monoclonal antibodyFeline
GM-Tg-cang-T89697-Ab-1/ GM-Tg-cang-T89697-Ab-2Anti-Canine IDO1 monoclonal antibodyCanine
GM-Tg-bovg-T89697-Ab-1/ GM-Tg-bovg-T89697-Ab-2Anti-Bovine IDO1 monoclonal antibodyBovine
GM-Tg-equg-T89697-Ab-1/ GM-Tg-equg-T89697-Ab-2Anti-Equine IDO1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg

Product Description

Catalog No.GM-Tg-hg-T89697-Ab-1/ GM-Tg-hg-T89697-Ab-2; GM-Tg-rg-T89697-Ab-1/ GM-Tg-rg-T89697-Ab-2;
GM-Tg-mg-T89697-Ab-1/ GM-Tg-mg-T89697-Ab-2; GM-Tg-cynog-T89697-Ab-1/ GM-Tg-cynog-T89697-Ab-2;
GM-Tg-felg-T89697-Ab-1/ GM-Tg-felg-T89697-Ab-2; GM-Tg-cang-T89697-Ab-1/ GM-Tg-cang-T89697-Ab-2;
GM-Tg-bovg-T89697-Ab-1/ GM-Tg-bovg-T89697-Ab-2; GM-Tg-equg-T89697-Ab-1/ GM-Tg-equg-T89697-Ab-2
Products NameAnti-IDO1 monoclonal antibody
Target NameIDO1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
Products descriptionPre-made anti-IDO1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T89697-Ag-1Recombinant multi-species I23O1/ IDO1/ IDO protein
    ORF Viral VectorpGMAD000139human IDO1 Adenovirus plasmid
    ORF Viral VectorpGMLV000300human IDO1 Lentivirus plasmid
    ORF Viral VectorvGMAD000139human IDO1 Adenovirus particle
    ORF Viral VectorvGMLV000300human IDO1 Lentivirus particle
    ORF Viral VectorpGMAD000210mouse Ido1 Adenovirus plasmid
    ORF Viral VectorpGMAD000453house mouse Ido1 Adenovirus plasmid
    ORF Viral VectorvGMAD000210mouse Ido1 Adenovirus particle
    ORF Viral VectorvGMAD000453house mouse Ido1 Adenovirus particle

    Target information

    Target IDGM-T89697
    Target NameIDO1
    Gene ID3620,15930,66029,574370,475574,101096977,506281,106782641
    Gene Symbol and SynonymsIDO,IDO-1,IDO1,INDO
    Uniprot AccessionP14902,Q9ERD9
    Uniprot Entry NameI23O1_HUMAN,I23O1_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target, Immuno-oncology Target
    Gene EnsemblENSG00000131203
    Target ClassificationCheckpoint-Immuno Oncology, Tumor-associated antigen (TAA)

    The target: IDO1, gene name: IDO1, also named as IDO, IDO-1, INDO. This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].

    About Gmab


    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.