Recombinant multi-species I23O1/ IDO1/ IDO protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IDO1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: IDO1, gene name: IDO1, also named as IDO, IDO-1, INDO. This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T89697-Ag-1	Human IDO1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T89697-Ag-1	Rat IDO1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T89697-Ag-1	Mouse IDO1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T89697-Ag-1	Cynomolgus/ Rhesus macaque IDO1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T89697-Ag-1	Feline IDO1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T89697-Ag-1	Canine IDO1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T89697-Ag-1	Bovine IDO1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T89697-Ag-1	Equine IDO1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T89697-Ag, GM-Tg-rg-T89697-Ag, GM-Tg-mg-T89697-Ag, GM-Tg-cynog-T89697-Ag, GM-Tg-felg-T89697-Ag, GM-Tg-cang-T89697-Ag, GM-Tg-bovg-T89697-Ag, GM-Tg-equg-T89697-Ag-1
Products Name	IDO1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	IDO1
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IDO1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.