ITLN1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of ITLN1. The page also collects GeneMedi's different modalities and formats products for ITLN1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ITLN1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

Enables calcium ion binding activity; identical protein binding activity; and oligosaccharide binding activity. Involved in positive regulation of glucose import; positive regulation of protein phosphorylation; and protein homotrimerization. Located in extracellular exosome. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]

Target IDGM-SE0290
Target NameITLN1
Gene ID55600,16429,498284
Gene Symbol and SynonymshIntL,HL-1,HL1,INTL,ITLN,ITLN1,Itln2,Itln3,Itln5,Itlna,LFR,omentin
Uniprot AccessionQ8WWA0
Uniprot Entry NameITLN1_HUMAN
Protein Sub-locationSecreted Protein/Potential Cytokines
CategoryCytokine Target
DiseaseN/A
Gene EnsemblENSG00000179914
Target ClassificationN/A


Pre-made anti-ITLN1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-ITLN1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ITLN1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-ITLN1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Cytokine antibodyDetail



Recombinant multi-species ITLN1/ HL-1/ HL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ITLN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
ITLN1 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Cytokine Products for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse intelectin 1 (galactofuranose binding) (ITLN1) His+Avi (Biotinylated) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Intelectin-1, also known as omentin or intestinal lactoferrin receptor, is an intelectin encoded in humans by the ITLN1 gene.Intelectin-1 functions both as a receptor for bacterial arabinogalactans and for lactoferrin.? Having conserved ligand binding site residues, both human and mouse intelectin-1 bind the exocyclic vicinal diol of carbohydrate ligands such as galactofuranose.

TargetSpeciesAntigen Product NameBioactivity validation of AntigenAntibody Product NameBioactivity validation of AntibodiesDetail
ITLN1Human, Cynomolgus/Rhesus macaque, rat, mouseintelectin 1 (galactofuranose binding) (ITLN1) proteinAffintiy&bioactivity validated by ELISA, cell culture validatedAnti-ITLN1 monoclonal antibodyBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).Detail

Click to check more Cytokine Products



Pre-made ITLN1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLP000058human ITLN1 Lentivirus plasmidNM_017625HumanLentivirus plasmidDetail
vGMLP000058human ITLN1 Lentivirus particleNM_017625HumanLentivirus particleDetail
pGMLPm000601mouse Itln1 Lentivirus plasmidNM_010584MouseLentivirus plasmidDetail
vGMLPm000601mouse Itln1 Lentivirus particleNM_010584MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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