SLPI: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of SLPI. The page also collects GeneMedi's different modalities and formats products for SLPI in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SLPI target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity. [provided by RefSeq, Nov 2014]
Target ID | GM-SE1292 |
Target Name | SLPI |
Gene ID | 6590,20568,711156,101090682 |
Gene Symbol and Synonyms | ALK1,ALP,BLPI,HUSI,HUSI-I,MPI,SLPI,WAP4,WFDC4 |
Uniprot Accession | P03973 |
Uniprot Entry Name | SLPI_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | Prostate Cancer |
Gene Ensembl | ENSG00000124107 |
Target Classification | N/A |
Pre-made anti-SLPI inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-SLPI benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SLPI mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-SLPI monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Recombinant multi-species SLPI/ ALK1/ ALP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SLPI protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
SLPI protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made SLPI viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLP000454 | human SLPI Lentivirus particle | NM_003064 | Human | Lentivirus particle | Detail |
vGMAP000268 | Human SLPI Adenovirus particle | BC020708 | Human | Adenovirus particle | Detail |
pGMLP000454 | human SLPI Lentivirus plasmid | NM_003064 | Human | Lentivirus plasmid | Detail |
pGMAP000268 | Human SLPI Adenovirus plasmid | BC020708 | Human | Adenovirus plasmid | Detail |
pGMAD000617 | house mouse Slpi Adenovirus plasmid | NM_011414 | House Mouse | Adenovirus plasmid | Detail |
pGMLPm000207 | mouse Slpi Lentivirus plasmid | NM_011414 | Mouse | Lentivirus plasmid | Detail |
vGMAD000617 | house mouse Slpi Adenovirus particle | NM_011414 | House Mouse | Adenovirus particle | Detail |
vGMLPm000207 | mouse Slpi Lentivirus particle | NM_011414 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.