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Anti-SLPI/ ALK1/ ALP functional antibody
Anti-SLPI/ ALK1/ ALP functional antibody for cell culture, ELISA & in-vivo assay
Go to SLPI/SLPI products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1292-Ab-1/ GM-Tg-hg-SE1292-Ab-2 | Anti-Human SLPI monoclonal antibody | Human |
| GM-Tg-rg-SE1292-Ab-1/ GM-Tg-rg-SE1292-Ab-2 | Anti-Rat SLPI monoclonal antibody | Rat |
| GM-Tg-mg-SE1292-Ab-1/ GM-Tg-mg-SE1292-Ab-2 | Anti-Mouse SLPI monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1292-Ab-1/ GM-Tg-cynog-SE1292-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLPI monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1292-Ab-1/ GM-Tg-felg-SE1292-Ab-2 | Anti-Feline SLPI monoclonal antibody | Feline |
| GM-Tg-cang-SE1292-Ab-1/ GM-Tg-cang-SE1292-Ab-2 | Anti-Canine SLPI monoclonal antibody | Canine |
| GM-Tg-bovg-SE1292-Ab-1/ GM-Tg-bovg-SE1292-Ab-2 | Anti-Bovine SLPI monoclonal antibody | Bovine |
| GM-Tg-equg-SE1292-Ab-1/ GM-Tg-equg-SE1292-Ab-2 | Anti-Equine SLPI monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1292-Ab-1/ GM-Tg-hg-SE1292-Ab-2; GM-Tg-rg-SE1292-Ab-1/ GM-Tg-rg-SE1292-Ab-2; GM-Tg-mg-SE1292-Ab-1/ GM-Tg-mg-SE1292-Ab-2; GM-Tg-cynog-SE1292-Ab-1/ GM-Tg-cynog-SE1292-Ab-2; GM-Tg-felg-SE1292-Ab-1/ GM-Tg-felg-SE1292-Ab-2; GM-Tg-cang-SE1292-Ab-1/ GM-Tg-cang-SE1292-Ab-2; GM-Tg-bovg-SE1292-Ab-1/ GM-Tg-bovg-SE1292-Ab-2; GM-Tg-equg-SE1292-Ab-1/ GM-Tg-equg-SE1292-Ab-2 |
| Products Name | Anti-SLPI monoclonal antibody |
| Format | mab |
| Target Name | SLPI |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLPI benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1292-Ag-1 | Recombinant multi-species SLPI/ ALK1/ ALP protein |
| ORF Viral Vector | vGMLP000454 | human SLPI Lentivirus particle |
| ORF Viral Vector | vGMAP000268 | Human SLPI Adenovirus particle |
| ORF Viral Vector | pGMLP000454 | human SLPI Lentivirus plasmid |
| ORF Viral Vector | pGMAP000268 | Human SLPI Adenovirus plasmid |
| ORF Viral Vector | pGMAD000617 | house mouse Slpi Adenovirus plasmid |
| ORF Viral Vector | pGMLPm000207 | mouse Slpi Lentivirus plasmid |
| ORF Viral Vector | vGMAD000617 | house mouse Slpi Adenovirus particle |
| ORF Viral Vector | vGMLPm000207 | mouse Slpi Lentivirus particle |
Target information
| Target ID | GM-SE1292 |
| Target Name | SLPI |
| Gene ID | 6590,20568,711156,101090682 |
| Gene Symbol and Synonyms | ALK1,ALP,BLPI,HUSI,HUSI-I,MPI,SLPI,WAP4,WFDC4 |
| Uniprot Accession | P03973 |
| Uniprot Entry Name | SLPI_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000124107 |
| Target Classification | N/A |
The target: SLPI, gene name: SLPI, also named as ALK1, ALP, BLPI, HUSI, HUSI-I, MPI, WAP4, WFDC4. This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity. [provided by RefSeq, Nov 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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