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It's the GeneMedi's summary page for Target/Biomarker Introduction of CDK12. The page also collects GeneMedi's different modalities and formats products for CDK12 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CDK12 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

Enables RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in phosphorylation of RNA polymerase II C-terminal domain; protein autophosphorylation; and regulation of MAP kinase activity. Located in nuclear speck. Part of cyclin K-CDK12 complex. [provided by Alliance of Genome Resources, Apr 2022]

Target IDGM-T08326
Target NameCDK12
Gene ID51755
Gene Official NameCDK12
Gene AliasCRK7, CRKR, CRKRS
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target


Pre-made anti-CDK12 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.

Pre-made anti-CDK12 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CDK12 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Cat No.Antibody NameFormatClassified by tagOrder
GM-Tg-hg-T08326-AbAnti-CDK12 monoclonal antibodymabTherapeutics Target antibodymonoclonal antibody.




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