GATA4: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of GATA4. The page also collects GeneMedi's different modalities and formats products for GATA4 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GATA4 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Target IDGM-T51817
Target NameGATA4
Gene ID2626,14463,54254,696775,486079,101086140,327716,100065126
Gene Symbol and SynonymsASD2,Gata-4,GATA4,TACHD,TOF,VSD1
Uniprot AccessionP43694,P46152,Q0Q0E4
Uniprot Entry NameGATA4_HUMAN,GATA4_RAT,GATA4_CANLF
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseHead and Neck Cancer
Gene EnsemblENSG00000136574
Target ClassificationN/A


Pre-made anti-GATA4 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-GATA4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GATA4 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-GATA4 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species GATA4/ ASD2/ TACHD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GATA4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
GATA4 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made GATA4 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMAD000115human GATA4 Adenovirus particleNM_002052.5HumanAdenovirus particleDetail
pGMAD000115human GATA4 Adenovirus plasmidNM_002052.5HumanAdenovirus plasmidDetail
pGMLV000028rat Gata4 Lentivirus plasmidNM_144730RatLentivirus plasmidDetail
pGMAAV000160rat Gata4 AAV plasmidNM_144730.1RatAAV plasmidDetail
pGMAAV000209house mouse Gata4 AAV plasmidNM_001310610House MouseAAV plasmidDetail
pGMAAV000268house mouse Gata4 AAV plasmidNM_001310610House MouseAAV plasmidDetail
pGMLPm004341mouse Gata4 Lentivirus plasmidNM_001310610MouseLentivirus plasmidDetail
vGMLV000028rat Gata4 Lentivirus particleNM_144730RatLentivirus particleDetail
vGMAAV000160rat Gata4 AAV particleNM_144730.1RatAAV particleDetail
vGMAAV000209house mouse Gata4 AAV particleNM_001310610House MouseAAV particleDetail
vGMAAV000268house mouse Gata4 AAV particleNM_001310610House MouseAAV particleDetail
vGMLPm004341mouse Gata4 Lentivirus particleNM_001310610MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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