PPAR-gamma/PPARG: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of PPAR-gamma/PPARG. The page also collects GeneMedi's different modalities and formats products for PPAR-gamma in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PPAR-gamma target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
|Gene Symbol and Synonyms||CIMT1,GLM1,NR1C3,PPAR-gamma,PPAR-gamma2,PPARG,PPARG1,PPARG2,PPARG5,PPARgamma,PPARgamma2|
|Uniprot Entry Name||PPARG_HUMAN,PPARG_MACMU,PPARG_RAT,PPARG_CANLF,PPARG_BOVIN|
|Protein Sub-location||Introcelluar Protein|
|Target Classification||Nuclear Receptors, Tumor-associated antigen (TAA)|
Pre-made anti-PPAR-gamma inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-PPAR-gamma monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PPAR-gamma mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
|Antibody Name||Species||Format||Classified by tag||Detail|
|Anti-PPAR-gamma/PPARG monoclonal antibody||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||mab||Therapeutics Target antibody||Detail|
Recombinant multi-species PPARG/ PPAR-gamma/ CIMT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPAR-gamma/PPARG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
|Products Name||Species||Expression Platform||Detail|
|PPAR-gamma/PPARG protein||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||Mammalian cell||Detail|
Pre-made PPARG viral vector in GM Promise-ORFTM
|Cat No.||Products name||NM ID||Species||Type||Detail|
|pGMAD000274||human PPARG Adenovirus plasmid||NM_015869.4||Human||Adenovirus plasmid||Detail|
|pGMAP000222||Human PPARG Adenovirus plasmid||BC006811||Human||Adenovirus plasmid||Detail|
|vGMAP000222||Human PPARG Adenovirus particle||BC006811||Human||Adenovirus particle||Detail|
|vGMAD000274||human PPARG Adenovirus particle||NM_015869.4||Human||Adenovirus particle||Detail|
|pGMLV000380||rat Pparg Lentivirus plasmid||NM_001145366.1||Rat||Lentivirus plasmid||Detail|
|pGMAD000070||rat Pparg Adenovirus plasmid||NM_001145366.1||Rat||Adenovirus plasmid||Detail|
|pGMAD000609||house mouse Pparg Adenovirus plasmid||NM_011146.3||House Mouse||Adenovirus plasmid||Detail|
|pGMLPm004023||mouse Pparg Lentivirus plasmid||NM_011146.3||Mouse||Lentivirus plasmid||Detail|
|pGMLPm005444||mouse Pparg Lentivirus plasmid||NM_013261.4||Mouse||Lentivirus plasmid||Detail|
|vGMLV000380||rat Pparg Lentivirus particle||NM_001145366.1||Rat||Lentivirus particle||Detail|
|vGMAD000070||rat Pparg Adenovirus particle||NM_001145366.1||Rat||Adenovirus particle||Detail|
|vGMAD000609||house mouse Pparg Adenovirus particle||NM_011146.3||House Mouse||Adenovirus particle||Detail|
|vGMLPm004023||mouse Pparg Lentivirus particle||NM_011146.3||Mouse||Lentivirus particle||Detail|
|vGMLPm005444||mouse Pparg Lentivirus particle||NM_013261.4||Mouse||Lentivirus particle||Detail|
|pGMLV000654||chicken PPARG Lentivirus plasmid||NM_001001460.1||Chicken||Lentivirus plasmid||Detail|
|vGMLV000654||chicken PPARG Lentivirus particle||NM_001001460.1||Chicken||Lentivirus particle||Detail|
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.