PPAR-gamma/PPARG: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of PPAR-gamma/PPARG. The page also collects GeneMedi's different modalities and formats products for PPAR-gamma in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PPAR-gamma target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

Target IDGM-T58921
Target NamePPAR-gamma
Gene ID5468,19016,25664,574190,403606,101095161,281993,100051258
Gene Symbol and SynonymsCIMT1,GLM1,NR1C3,PPAR-gamma,PPAR-gamma2,PPARG,PPARG1,PPARG2,PPARG5,PPARgamma,PPARgamma2
Uniprot AccessionP37231,O88275,O18924,Q4U3Q4,O18971
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
Gene EnsemblENSG00000132170
Target ClassificationNuclear Receptors, Tumor-associated antigen (TAA)

Pre-made anti-PPAR-gamma inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-PPAR-gamma monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PPAR-gamma mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-PPAR-gamma/PPARG monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail

Recombinant multi-species PPARG/ PPAR-gamma/ CIMT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPAR-gamma/PPARG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
PPAR-gamma/PPARG proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail

Pre-made PPARG viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMAD000274human PPARG Adenovirus plasmidNM_015869.4HumanAdenovirus plasmidDetail
pGMAP000222Human PPARG Adenovirus plasmidBC006811HumanAdenovirus plasmidDetail
vGMAP000222Human PPARG Adenovirus particleBC006811HumanAdenovirus particleDetail
vGMAD000274human PPARG Adenovirus particleNM_015869.4HumanAdenovirus particleDetail
pGMLV000380rat Pparg Lentivirus plasmidNM_001145366.1RatLentivirus plasmidDetail
pGMAD000070rat Pparg Adenovirus plasmidNM_001145366.1RatAdenovirus plasmidDetail
pGMAD000609house mouse Pparg Adenovirus plasmidNM_011146.3House MouseAdenovirus plasmidDetail
pGMLPm004023mouse Pparg Lentivirus plasmidNM_011146.3MouseLentivirus plasmidDetail
pGMLPm005444mouse Pparg Lentivirus plasmidNM_013261.4MouseLentivirus plasmidDetail
vGMLV000380rat Pparg Lentivirus particleNM_001145366.1RatLentivirus particleDetail
vGMAD000070rat Pparg Adenovirus particleNM_001145366.1RatAdenovirus particleDetail
vGMAD000609house mouse Pparg Adenovirus particleNM_011146.3House MouseAdenovirus particleDetail
vGMLPm004023mouse Pparg Lentivirus particleNM_011146.3MouseLentivirus particleDetail
vGMLPm005444mouse Pparg Lentivirus particleNM_013261.4MouseLentivirus particleDetail
pGMLV000654chicken PPARG Lentivirus plasmidNM_001001460.1ChickenLentivirus plasmidDetail
vGMLV000654chicken PPARG Lentivirus particleNM_001001460.1ChickenLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.

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