ESRRA: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of ESRRA. The page also collects GeneMedi's different modalities and formats products for ESRRA in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ESRRA target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1. [provided by RefSeq, Jun 2019]
Target ID | GM-T72841 |
Target Name | ESRRA |
Gene ID | 2101,26379,293701,722085,403169,101099657,507834,100055615 |
Gene Symbol and Synonyms | ERR1,ERRa,ERRalpha,Errra,ESRL1,ESRRA,Estrra,NR3B1 |
Uniprot Accession | P11474,Q5QJV7,Q6QMY5 |
Uniprot Entry Name | ERR1_HUMAN,ERR1_RAT,ERR1_CANLF |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000173153 |
Target Classification | Nuclear Receptors |
Pre-made anti-ESRRA inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-ESRRA monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ESRRA mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-ESRRA monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species ERR1/ ESRRA/ ERRa protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ESRRA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
ESRRA protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made ESRRA viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMAD000107 | human ESRRA Adenovirus plasmid | NM_001282451 | Human | Adenovirus plasmid | Detail |
vGMAD000107 | human ESRRA Adenovirus particle | NM_001282451 | Human | Adenovirus particle | Detail |
pGMAAV000283 | house mouse Esrra AAV plasmid | NM_007953.2 | House Mouse | AAV plasmid | Detail |
pGMAAV000355 | house mouse Esrra AAV plasmid | NM_007953 | House Mouse | AAV plasmid | Detail |
pGMLPm004325 | mouse Esrra Lentivirus plasmid | NM_007953 | Mouse | Lentivirus plasmid | Detail |
vGMAAV000283 | house mouse Esrra AAV particle | NM_007953.2 | House Mouse | AAV particle | Detail |
vGMAAV000355 | house mouse Esrra AAV particle | NM_007953 | House Mouse | AAV particle | Detail |
vGMLPm004325 | mouse Esrra Lentivirus particle | NM_007953 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.