MLTK/MAP3K20: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of MLTK/MAP3K20. The page also collects GeneMedi's different modalities and formats products for MLTK in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the MLTK target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Target IDGM-T97821
Target NameMLTK
Gene ID51776,65964,311743,698274,478802,101094038,519251,100053153
Gene Symbol and SynonymsAZK,B230120H23Rik,CNM6,HCCS-4,MAP3K20,MLK7,mlklak,MLT,MLTK,MLTKalpha,MLTKbeta,MRK,pk,RGD1561394,SFMMP,ZAK
Uniprot AccessionQ9NYL2
Uniprot Entry NameM3K20_HUMAN
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseN/A
Gene EnsemblENSG00000091436
Target ClassificationKinase


Pre-made anti-MLTK inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-MLTK monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-MLTK mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-MLTK/MAP3K20 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species M3K20/ MLTK/ MAP3K20 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MLTK/MAP3K20 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
MLTK/MAP3K20 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made MAP3K20 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP001317human MAP3K20 Lentivirus particleNM_016653HumanLentivirus particleDetail
pGMLP001317human MAP3K20 Lentivirus plasmidNM_016653HumanLentivirus plasmidDetail
pGMLPm004102mouse Map3k20 Lentivirus plasmidNM_023057MouseLentivirus plasmidDetail
vGMLPm004102mouse Map3k20 Lentivirus particleNM_023057MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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