Pre-made Apitegromab benchmark antibody ( Whole mAb, anti-pro-GDF-8 therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-030

Pre-Made Apitegromab biosimilar, Whole Mab: Anti-pro-GDF-8 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Apitegromab (SRK 015) is an anti-promyostatin monoclonal antibody that is being developed by Scholar Rock, for the treatment of spinal muscular atrophy (SMA), muscle-wasting disorders and spinal cord injuries.

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GMP-Bios-ab-030-1mg 1mg 3090 Inquiry Inquiry

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Apitegromab biosimilar, Whole Mab: Anti-pro-GDF-8 therapeutic antibody
INN Name Apitegromab
Targetpro-GDF-8
FormatWhole mAb
Derivation
Species ReactivityHuman
CH1 IsotypeIgG4
VD LCLambda
Highest_Clin_Trial (Jan '20)Phase-II
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI Structure6umx:HL:hl
Year Proposed2020
Year Recommended2021
CompaniesScholar Rock
Conditions Approvedna
Conditions ActiveSpinal muscular atrophy;Muscular atrophy;Spinal cord injuries
Conditions Discontinuedna
Development Techna