Pre-made Briakinumab benchmark antibody ( Whole mAb, anti-IL12B therapeutic antibody, Anti-CLMF/CLMF2/IL-12B/IMD28/IMD29/NKSF/NKSF2 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-081

Pre-Made Briakinumab biosimilar, Whole mAb, Anti-IL12B Antibody: Anti-CLMF/CLMF2/IL-12B/IMD28/IMD29/NKSF/NKSF2 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Briakinumab (ABT-874) is a human monoclonal antibody being developed by Abbott Laboratories for the treatment of rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis. As of 2011 drug development for psoriasis has been discontinued in the U.S. and Europe.

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GMP-Bios-ab-081-1mg 1mg 3090 Inquiry Inquiry

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Briakinumab biosimilar, Whole mAb, Anti-IL12B Antibody: Anti-CLMF/CLMF2/IL-12B/IMD28/IMD29/NKSF/NKSF2 therapeutic antibody
INN Name Briakinumab
TargetIL12B
FormatWhole mAb
DerivationHuman
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCLambda
Highest_Clin_Trial (Jan '20)Preregistration (w)
Est. StatusDiscontinued
100% SI Structure5n2k:LK:BA:PO:DC:NM:FE
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2009
Year Recommended2010
CompaniesCambridge Antibody Technology;Abbott GmbH & Co. KG
Conditions Approvedna
Conditions Activena
Conditions DiscontinuedPlaque psoriasis;Crohn's disease;Multiple sclerosis;Rheumatoid arthritis
Development Techna