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Anti-Ganglioside GD2 therapeutic antibody (Pre-made Dinutuximab biosimilar,Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).

Dinutuximab (Ch14.18, tradename Unituxin) and Dinutuximab beta (tradename Qarziba) are monoclonal antibodies used as a second-line treatment for children with high-risk neuroblastoma. Each antibody is made of both mouse and human components and targets glycolipid GD2, expressed on neuroblastoma cells and on normal cells of neuroectodermal origin, including the central nervous system and peripheral nerves. They differ in that dinutuximab is manufactured using mouse cells, and dinutuximab beta is manufactured using hamster cells. The dosing regime differs, and dinutuximab is given in combination with granulocyte-macrophage colony stimulating factor (GM-CSF), interleukin-2 (IL-2) and 13-cis-retinoic acid (RA), while dinutuximab beta can be given alone.

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Delivery impact due to the Coronavirus Outbreak

With the COVID-19 outbreak in the world, many flights have been cancelled. In order for the customer to receive the goods properly, we use the FedEx Customized Freight (FCF) of Fedex which demands a higher fee. If the delivery fee is more expensive in your area, we will contact you by mail.

Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-ab-146-1mg 1mg 3090
GMP-Bios-ab-146-10mg 10mg 21890
GMP-Bios-ab-146-100mg 100mg 148000
GMP-Bios-ab-146-xmg ≥100mg Inquiry
Shipping Cost: 760.00


Products Name (INN Index) Anti-Ganglioside GD2 therapeutic antibody (Pre-made Dinutuximab biosimilar,Whole mAb)
INN Name Dinutuximab
TargetGanglioside GD2
FormatWhole mAb
DerivationChimeric (Mouse/Human)
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Approved
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI Structure4tuj:CD:AB/4tul:HL/4trp:HL/4tuo:AB:CD/4tuk:HL
Year Proposed2013
Year Recommended2014
CompaniesNational Cancer Institute (USA);New Approaches to Neuroblastoma Therapy Consortium;St. John of God Foundation;United Therapeutics Corporation
Conditions ApprovedNeuroblastoma
Conditions ActiveSmall cell lung cancer
Conditions DiscontinuedMalignant melanoma
Development Techna