Pre-made Ieramilimab benchmark antibody ( Whole mAb, anti-CD223/LAG3 therapeutic antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-262

Pre-Made Ieramilimab biosimilar, Whole Mab: Anti-CD223/LAG3 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Ieramilimab (development code LAG525) is a monoclonal antibody being developed by Novartis for the treatment of cancer. The antibody targets the immune checkpoint LAG-3, which is expressed on T cells and tends to down-regulate an immune response. In a June 2015 presentation Novartis management indicated that 'dosing is imminent' for the first clinical trials of LAG525.

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Catalog No. Package List Price(In USD) Discount off Discount Price
GMP-Bios-ab-262-1mg 1mg 3090 30% 2163

Size: 1mg | 10mg | 100mg


Products Name (INN Index) Pre-Made Ieramilimab biosimilar, Whole Mab: Anti-CD223/LAG3 therapeutic antibody
INN Name Ieramilimab
FormatWhole mAb
Species ReactivityHuman
CH1 IsotypeIgG4
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-II
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2018
Year Recommended2019
CompaniesImmutep Limited;Novartis
Conditions Approvedna
Conditions ActiveBreast cancer;Diffuse large B cell lymphoma;Malignant melanoma;Solid tumours
Conditions Discontinuedna
Development Techna