Pre-made Narnatumab benchmark antibody ( Whole mAb, anti-MST1R/RON therapeutic antibody, Anti-RON/SEA/PTK8/CD136/NPCA3/CDw136 Antibody) for drug discovery and mechanism of action (MOA) research

Cat No.: GMP-Bios-ab-365

Pre-Made Narnatumab biosimilar, Whole mAb, Anti-MST1R/RON Antibody: Anti-RON/SEA/PTK8/CD136/NPCA3/CDw136 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Narnatumab is a human monoclonal antibody designed for the treatment of cancer.[1] Clinical development was abandoned after phase I trials.

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GMP-Bios-ab-365-1mg 1mg 3090 Inquiry Inquiry

Size: 1mg | 10mg | 100mg



Description

Products Name (INN Index) Pre-Made Narnatumab biosimilar, Whole mAb, Anti-MST1R/RON Antibody: Anti-RON/SEA/PTK8/CD136/NPCA3/CDw136 therapeutic antibody
INN Name Narnatumab
TargetRON
FormatWhole mAb
DerivationHuman
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Phase-I
Est. StatusDiscontinued
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2011
Year Recommended2012
CompaniesImClone Systems;Eli Lilly;ImClone Systems
Conditions Approvedna
Conditions Activena
Conditions DiscontinuedSolid tumours
Development Techna