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Anti-CSF2 therapeutic antibody (Pre-made Otilimab biosimilar,Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).

Otilimab (development codes MOR103 and GSK3196165) is a fully human antibody which has been developed by the biotechnology company MorphoSys. It can also be referred to as HuCAL antibody, HuCAL standing for Human Combinatorial Antibody Library and being a technology used to generate monoclonal antibodies. Otilimab is directed against the granulocyte-macrophage colony stimulating factor (GM-CSF), a monomeric glycoprotein functioning as a cytokine promoting both proliferation and activation of macrophages and neutrophils.

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Delivery impact due to the Coronavirus Outbreak

With the COVID-19 outbreak in the world, many flights have been cancelled. In order for the customer to receive the goods properly, we use the FedEx Customized Freight (FCF) of Fedex which demands a higher fee. If the delivery fee is more expensive in your area, we will contact you by mail.

Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-ab-415-1mg 1mg 3090
GMP-Bios-ab-415-10mg 10mg 21890
GMP-Bios-ab-415-100mg 100mg 148000
GMP-Bios-ab-415-xmg >100mg Inquiry
Shipping Cost: 760.00
Total:



Description

Products Name (INN Index) Anti-CSF2 therapeutic antibody (Pre-made Otilimab biosimilar,Whole mAb)
INN Name Otilimab
TargetCSF2
FormatWhole mAb
DerivationHuman
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCLambda
Highest_Clin_Trial (Jan '20)Phase-III
Est. StatusActive
100% SI StructureNone
99% SI Structure5c7x:MN:HL/5d7s:HL
95-98% SI Structure5d72:MN:HL/5d71:HL
Year Proposed2018
Year Recommended2019
CompaniesGlaxoSmithKline;MorphoSys
Conditions Approvedna
Conditions ActiveRheumatoid arthritis
Conditions DiscontinuedInflammation;Multiple sclerosis;Osteoarthritis
Development TechMorphoSys HuCAL Phage Display