
Pre-made Relfovetmab benchmark antibody ( Feline Whole mAb, anti-NGFB/NGF therapeutic antibody, Anti-HSAN5 Antibody) for drug discovery and mechanism of action (MOA) research
Cat No.: GMP-Bios-ab-477
Pre-Made Relfovetmab biosimilar, Feline Whole mAb, Anti-NGFB/NGF Antibody: Anti-HSAN5 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Reslizumab is a humanized monoclonal antibody against human interleukin-5 (IL-5). Reslizumab binds specifically to IL-5, a key cytokine responsible for the differentiation, maturation, recruitment and activation of human eosinophils. By binding to human IL-5, it blocks its biological function; consequently survival and activity of eosinophils are reduced. The benefits with reslizumab are its ability to reduce the exacerbation rate and improve lung function and asthma-related quality of life in patients with severe eosinophilic asthma (with blood eosinophil count ≥ 400 cells/μL) and with at least one previous asthma exacerbation in the preceding year. The most common side effects are increased blood creatine phosphokinase, myalgia and anaphylactic reactions.
Order information
Delivery impact due to the Coronavirus Outbreak
With the COVID-19 outbreak in the world, many flights have been cancelled. In order for the customer to receive the goods properly, we use the FedEx Customized Freight (FCF) of Fedex which demands a higher fee. If the delivery fee is more expensive in your area, we will contact you by mail.
Catalog No. | Package | Price(In USD) | Qty (Quantity) | Sum(In USD) |
---|---|---|---|---|
GMP-Bios-ab-477-1mg | 1mg | 3090 | ||
GMP-Bios-ab-477-10mg | 10mg | 21890 | ||
GMP-Bios-ab-477-100mg | 100mg | 148000 | ||
GMP-Bios-ab-477-xmg | ≥100mg | Inquiry | ||
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Products Name (INN Index) | Pre-Made Relfovetmab biosimilar, Feline Whole mAb, Anti-NGFB/NGF Antibody: Anti-HSAN5 therapeutic antibody |
INN Name | Relfovetmab |
Target | NGF |
Format | Feline Whole mAb |
Derivation | Felinized |
Species Reactivity | Feline |
CH1 Isotype | IgG1 |
VD LC | Kappa |
Highest_Clin_Trial (Jan '20) | Unknown |
Est. Status | Active |
100% SI Structure | None |
99% SI Structure | None |
95-98% SI Structure | None |
Year Proposed | 2018 |
Year Recommended | 2019 |
Companies | na |
Conditions Approved | na |
Conditions Active | na |
Conditions Discontinued | na |
Development Tech | na |
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