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About COVID-19 pandemic, Coronavirus (Coronavirus) and genome of SARS-CoV-2 (2019nCoV)

COVID-19 pandemic is caused by 2019nCoV (SARS-CoV-2, a novel coronavirus) infection.The 2019-nCoV genome was annotated to possess 14 ORFs encoding 27 proteins1.

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Figure. Schematic representative of genome structure and encoded gene of SARS-CoV-2 (2019nCoV)1

Table.Genome Annotation of 2019-nCoV1
Gene name of 2019nCoV (SARS-CoV-2, a novel coronavirus) Coding region(nt) Protein length(aa)
orf1a266-134834405
orf1ab266-13468, 13468-215557096
S21563-253841273
3a25393-26220275
3b25814-2588222
26183-2628132
E (envelope protei)26245-2647275
M (matrix protein)26523-27191222
p627202-2738761
7a27394-27759121
7b27756-2788743
8b27894-28259121
9b28284-2857797
N(nucleocapsid)28274-29533419
orf1428734-2895573

Collection of COVID-19 landscape knowledge base


Viral vector-based vaccine; DNA-based vaccine; RNA based vaccine - A landscape for vaccine technology against infectious disease, COVID-19 and tumor.

COVID-19 landscape Knowledge Base



References

1. Wu, A. et al. Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China. Cell Host Microbe, doi:10.1016/j.chom.2020.02.001 (2020).




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