Human PI3/cementoin/ESI ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_002638.4)

Cat. No.: pGMAAV000494
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PI3/cementoin/ESI Adeno-associated virus expression plasmid (ITR-vector) for PI3 AAV packaging, PI3 AAV production.The purified Human PI3/cementoin/ESI AAV particle serves as an invaluable asset for in-depth in vivo PI3 studies, mechanism of action (MOA) research, and the evolution of PI3-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV000494
Gene Name PI3
Accession Number NM_002638.4
Gene ID 5266
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 354 bp
Gene Alias cementoin,ESI,SKALP,WAP3,WFDC14
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAGGGCCAGCAGCTTCTTGATCGTGGTGGTGTTCCTCATCGCTGGGACGCTGGTTCTAGAGGCAGCTGTCACGGGAGTTCCTGTTAAAGGTCAAGACACTGTCAAAGGCCGTGTTCCATTCAATGGACAAGATCCCGTTAAAGGACAAGTTTCAGTTAAAGGTCAAGATAAAGTCAAAGCGCAAGAGCCAGTCAAAGGTCCAGTCTCCACTAAGCCTGGCTCCTGCCCCATTATCTTGATCCGGTGCGCCATGTTGAATCCCCCTAACCGCTGCTTGAAAGATACTGACTGCCCAGGAATCAAGAAGTGCTGTGAAGGCTCTTGCGGGATGGCCTGTTTCGTTCCCCAGTGA
ORF Protein Sequence MRASSFLIVVVFLIAGTLVLEAAVTGVPVKGQDTVKGRVPFNGQDPVKGQVSVKGQDKVKAQEPVKGPVSTKPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMACFVPQ

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0406-Ab Anti-ELAF/ PI3/ ESI functional antibody
    Target Antigen GM-Tg-g-SE0406-Ag PI3 protein
    ORF Viral Vector pGMLP004215 Human PI3 Lentivirus plasmid
    ORF Viral Vector pGMAAV000494 Human PI3 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector vGMLP004215 Human PI3 Lentivirus particle
    ORF Viral Vector vGMAAV000494 Human PI3 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-SE0406
    Target Name PI3
    Gene ID 5266, 574237, 101090932, 477241, 100056125
    Gene Symbol and Synonyms cementoin,ESI,PI3,SKALP,TRAPPIN-2,WAP3,WFDC14
    Uniprot Accession P19957
    Uniprot Entry Name ELAF_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Ovary Cancer
    Gene Ensembl ENSG00000124102
    Target Classification Not Available

    This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.