Human MECP2/AUTSX3/ MRX16 ORF/cDNA clone-Adenovirus plasmid (NM_004992.3)

Pre-made Human MECP2/AUTSX3/ MRX16 adenoviral expression plasmid for MECP2 adenovirus packaging, MECP2 adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

Target products collectionGo to MECP2/AUTSX3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMAD000175 Human MECP2 Adenovirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMAD000175
Gene Name MECP2
Accession Number NM_004992.3
Gene ID 4204
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 1461 bp
Gene Alias AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT
Fluorescent Reporter
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T59686-Ab Anti-MECP2 monoclonal antibody
    Target Antigen GM-Tg-g-T59686-Ag MECP2 protein
    ORF Viral Vector pGMAD000175 Human MECP2 Adenovirus plasmid
    ORF Viral Vector pGMPC000469 Human MECP2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMAP000464 Human MECP2 Adenovirus plasmid
    ORF Viral Vector vGMAD000175 Human MECP2 Adenovirus particle
    ORF Viral Vector vGMAP000464 Human MECP2 Adenovirus particle


    Target information

    Target ID GM-T59686
    Target Name MECP2
    Gene ID 4204, 17257, 700174, 29386, 101082385, 612973, 539629, 100058125
    Gene Symbol and Synonyms 1500041B07Rik,AUTSX3,D630021H01Rik,Mbd5,MECP2,MRX16,MRX79,MRXS13,MRXSL,PPMX,RS,RTS,RTT,WBP10
    Uniprot Accession P51608
    Uniprot Entry Name MECP2_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000169057
    Target Classification Tumor-associated antigen (TAA)

    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of cognitive disability in females. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.