Human IL16/LCF/NIL16 ORF/cDNA clone-Lentivirus plasmid (NM_004513)

Cat. No.: pGMLP-IL-019
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human IL16/LCF/NIL16 Lentiviral expression plasmid for IL16 lentivirus packaging, IL16 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP-IL-019
Gene Name IL16
Accession Number NM_004513
Gene ID 3603
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1896 bp
Gene Alias LCF,NIL16,prIL-16,PRIL16
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGACTATAGCTTTGATACCACAGCCGAAGACCCTTGGGTTAGGATTTCTGACTGCATCAAAAACTTATTTAGCCCCATCATGAGTGAGAACCATGGCCACATGCCTCTACAGCCCAATGCCAGCCTGAATGAAGAAGAAGGGACACAGGGCCACCCAGATGGGACCCCACCAAAGCTGGACACCGCCAATGGCACTCCCAAAGTTTACAAGTCAGCAGACAGCAGCACTGTGAAGAAAGGTCCTCCTGTGGCTCCCAAGCCAGCCTGGTTTCGCCAAAGCTTGAAAGGTTTGAGGAATCGTGCTTCAGACCCAAGAGGGCTCCCTGATCCTGCCTTGTCCACCCAGCCAGCACCTGCTTCCAGGGAGCACCTAGGATCACACATCCGGGCCTCCTCCTCCTCCTCCTCCATCAGGCAGAGAATCAGCTCCTTTGAAACCTTTGGCTCCTCTCAACTGCCTGACAAAGGAGCCCAGAGACTGAGCCTCCAGCCCTCCTCTGGGGAGGCAGCAAAACCTCTTGGGAAGCATGAGGAAGGACGGTTTTCTGGACTCTTGGGGCGAGGGGCTGCACCCACTCTTGTGCCCCAGCAGCCTGAGCAAGTACTGTCCTCGGGGTCCCCTGCAGCCTCCGAGGCCAGAGACCCAGGTGTGTCTGAGTCCCCTCCCCCAGGGCGGCAGCCCAATCAGAAAACTCTCCCCCCTGGCCCGGACCCGCTCCTAAGGCTGCTGTCAACACAGGCTGAGGAATCTCAAGGCCCAGTGCTCAAGATGCCTAGCCAGCGAGCACGGAGCTTCCCCCTGACCAGGTCCCAGTCCTGTGAGACGAAGCTACTTGACGAAAAGACCAGCAAACTCTATTCTATCAGCAGCCAAGTGTCATCGGCTGTCATGAAATCCTTGCTGTGCCTTCCATCTTCTATCTCCTGTGCCCAGACTCCCTGCATCCCCAAGGAAGGGGCATCTCCAACATCATCATCCAACGAAGACTCAGCTGCAAATGGTTCTGCTGAAACATCTGCCTTGGACACAGGGTTCTCGCTCAACCTTTCAGAGCTGAGAGAATATACAGAGGGTCTCACGGAAGCCAAGGAAGACGATGATGGGGACCACAGTTCCCTTCAGTCTGGTCAGTCCGTTATCTCCCTGCTGAGCTCAGAAGAATTAAAAAAACTCATCGAGGAGGTGAAGGTTCTGGATGAAGCAACATTAAAGCAATTAGACGGCATCCATGTCACCATCTTACACAAGGAGGAAGGTGCTGGTCTTGGGTTCAGCTTGGCAGGAGGAGCAGATCTAGAAAACAAGGTGATTACGGTTCACAGAGTGTTTCCAAATGGGCTGGCCTCCCAGGAAGGGACTATTCAGAAGGGCAATGAGGTTCTTTCCATCAACGGCAAGTCTCTCAAGGGGACCACGCACCATGATGCCTTGGCCATCCTCCGCCAAGCTCGAGAGCCCAGGCAAGCTGTGATTGTCACAAGGAAGCTGACTCCAGAGGCCATGCCCGACCTCAACTCCTCCACTGACTCTGCAGCCTCAGCCTCTGCAGCCAGTGATGTTTCTGTAGAATCTACAGCAGAGGCCACAGTCTGCACGGTGACACTGGAGAAGATGTCGGCAGGGCTGGGCTTCAGCCTGGAAGGAGGGAAGGGCTCCCTACACGGAGACAAGCCTCTCACCATTAACAGGATTTTCAAAGGAGCAGCCTCAGAACAAAGTGAGACAGTCCAGCCTGGAGATGAAATCTTACAGCTGGGTGGCACTGCCATGCAGGGCCTCACACGGTTTGAAGCCTGGAACATCATCAAGGCACTGCCTGATGGACCTGTCACGATTGTCATCAGGAGAAAAAGCCTCCAGTCCAAGGAAACCACAGCTGCTGGAGACTCCTAG
ORF Protein Sequence MDYSFDTTAEDPWVRISDCIKNLFSPIMSENHGHMPLQPNASLNEEEGTQGHPDGTPPKLDTANGTPKVYKSADSSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRGLPDPALSTQPAPASREHLGSHIRASSSSSSIRQRISSFETFGSSQLPDKGAQRLSLQPSSGEAAKPLGKHEEGRFSGLLGRGAAPTLVPQQPEQVLSSGSPAASEARDPGVSESPPPGRQPNQKTLPPGPDPLLRLLSTQAEESQGPVLKMPSQRARSFPLTRSQSCETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQTPCIPKEGASPTSSSNEDSAANGSAETSALDTGFSLNLSELREYTEGLTEAKEDDDGDHSSLQSGQSVISLLSSEELKKLIEEVKVLDEATLKQLDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTAAGDS

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T51698-Ab Anti-IL16/ LCF/ NIL16 monoclonal antibody
    Target Antigen GM-Tg-g-T51698-Ag IL16 VLP (virus-like particle)
    ORF Viral Vector pGMLP-IL-019 Human IL16 Lentivirus plasmid
    ORF Viral Vector pGMAP-IL-102 Human IL16 Adenovirus plasmid
    ORF Viral Vector vGMLP-IL-019 Human IL16 Lentivirus particle
    ORF Viral Vector vGMAP-IL-102 Human IL16 Adenovirus particle


    Target information

    Target ID GM-T51698
    Target Name IL16
    Gene ID 3603, 16170, 574100, 116996, 493882, 488762, 506314, 100067252
    Gene Symbol and Synonyms IL-16,IL16,LCF,mKIAA4048,NIL16,prIL-16,PRIL16
    Uniprot Accession Q14005
    Uniprot Entry Name IL16_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease myeloma
    Gene Ensembl ENSG00000172349
    Target Classification Not Available

    The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]



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